Toxoplasma gondii infection in goats: serological, pathological, and clinical monitoring during gestation

被引：3

作者：

Baltazar de Oliveira, Junior Mario ^{[1
]}

Pajeu e Silva, Bruno ^{[1
]}

Ribeiro-Andrade, Muller ^{[2
]}

Nascimento Porto, Wagnner Jose ^{[2
]}

Bandeira de Melo, Renata Pimentel ^{[1
]}

Pinheiro Junior, Jose Wilton ^{[1
]}

da Fonseca Oliveira, Andrea Alice ^{[1
]}

Mota, Rinaldo Aparecido ^{[1
]}

机构：

[1] Univ Fed Rural Pernambuco, Dept Vet Med, Rua Dom Manoel de Medeiros, BR-52171900 Recife, PE, Brazil

[2] Univ Fed Alagoas, Inst Biol Sci & Hlth, Av Lourival Melo Mota, BR-57072900 Maceio, Alagoas, Brazil

来源：

PARASITOLOGY RESEARCH | 2022年 / 121卷 / 11期

关键词：

Caprine; Toxoplasmosis; Reproductive loss; Abortion; Pregnant goats; NEOSPORA-CANINUM INFECTIONS; RISK-FACTORS; SMALL RUMINANTS; OVINE; SEROPREVALENCE; ABORTION; ANTIBODIES; STRAIN;

D O I：

10.1007/s00436-022-07633-1

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

This study aimed to evaluate Toxoplasma gondii infection in pregnant goats. The goats were divided into two groups: group one (G1) comprised of 31 pregnant goats naturally infected with T. gondii, and group two (G2) comprised of seven uninfected pregnant goats from a flock with a history of abortion due to toxoplasmosis. Serological investigation, ultrasonography, and clinical testing were performed on all goats during gestation. Serum samples from goats and their offspring (precolostral) were collected to evaluate the vertical transmission of T. gondii. Samples from placentas and aborted fetuses were also collected for molecular and histopathological analysis. Results showed that in G1, estrus recurrence occurred in 22.6% (7/31) of the goats, embryonic death in 3.3% (1/31), and abortion in 19.4% (6/31). An increase in anti-T. gondii antibodies was observed in G1 goats at day 150 of pregnancy. T. gondii DNA was detected in 42.8% (3/7) of aborted fetuses and was associated with histopathological lesions caused by this parasite. Moreover, toxoplasmosis in field conditions caused by genotype ToxoDB #1 in pregnant goats resulted in severe reproductive loss in the flock.

引用

页码：3147 / 3153

页数：7

共 34 条

[1] Influence of age and purpose for testing on the cut-off selection of serological methods in bovine neosporosis [J].