Two New Flavones from Cassia pumila and Their Anti-Tobacco Mosaic Virus Activity

被引：8

作者：

Kong, Wei-Song ^{[1
]}

Xing, Huan-Huan ^{[1
,2
]}

Li, Jing ^{[1
]}

Ye, Lin ^{[1
]}

Liu, Xin ^{[1
]}

Li, Yan-Ping ^{[4
]}

Rao, Gao-Xiong ^{[4
]}

Zhou, Min ^{[1
]}

Guangyu-Yang ^{[1
]}

Hu, Qiu-Fen ^{[1
,2
]}

Li, Yin-Ke ^{[1
,3
]}

Li, Xue-Mei ^{[1
]}

机构：

[1] China Tobacco Yunnan Ind Co Ltd, Kunming 650231, Yunnan, Peoples R China

[2] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, Kunming 650031, Yunnan, Peoples R China

[3] Yuxi Normal Univ, Coll Resource & Environm, Yuxi 653100, Peoples R China

[4] Yunnan Univ Tradit Chinese Med, Coll Pharmaceut Sci, Kunming 650500, Yunnan, Peoples R China

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2018年 / 54卷 / 06期

基金：

中国国家自然科学基金;

关键词：

flavones; Cassia pumila; anti-tobacco mosaic virus (anti-TMV) activity; FISTULA; SIAMEA; DERIVATIVES; STEMS; BARK; BIOACTIVITIES; ALKALOIDS; CHROMONES; SEEDS;

D O I：

10.1007/s10600-018-2552-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new flavones, 8-hydroxy-7-(3-hydroxypropyl)-2-methoxyflavone (1) and 8-hydroxy-7-(2-hydroxyethyl)-2-methoxyflavone (2), together with four known flavones (3-6), were isolated from the whole plants of Cassia pumila. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 have potential anti-TMV activities with inhibition rates of 30.2% and 28.2%, respectively.

引用

页码：1048 / 1051

页数：4

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