Electrical Properties of Hydrogenated Planar Lipid Bilayers Formed from Archaea Lipids at Different Temperatures

被引：0
|
作者：
Velikonja, Aljaz [1 ]
Kramar, Peter [1 ]
Miklavcic, Damijan [1 ]
Lebar, Alenka Macek [1 ]
机构：
[1] Univ Ljubljana, Fac Elect Engn, SI-1000 Ljubljana, Slovenia
来源：
6TH EUROPEAN CONFERENCE OF THE INTERNATIONAL FEDERATION FOR MEDICAL AND BIOLOGICAL ENGINEERING | 2015年 / 45卷
关键词：
planar lipid bilayers; temperature; archaeal lipids; electrical capacitance; breakdown voltage; MOLECULAR-DYNAMICS SIMULATION; PHYSICOCHEMICAL PROPERTIES; PHASE-TRANSITIONS; MEMBRANES; ELECTROPORATION;
D O I：
10.1007/978-3-319-11128-5_139
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
This paper presents the study of electrical properties of hydrogenated planar lipid bilayers formed from thermophilic archaeal lipids extracted from Aeropyrum pernix K1. Study is focused on measuring electrical capacitance as parameter of the planar lipid bilayer thickness and breakdown voltage as parameter of planar lipid bilayer stability in electric field. The results show that both measured parameters of hydrogenated planar lipid bilayers formed from archeal lipids extracted from A. pernix K1 are not temperature dependant on measured temperature interval between 19 degrees C and 56 degrees C. Electrical capacitance is lower than in Molecular Dynamic simulations and in experiments using 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine (POPC) lipids or 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphoserine (POPS) lipids. Breakdown voltage is higher than in experiments with POPC or POPS lipids.
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页码：557 / 560
页数：4
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