Vigilance for veterinary medicinal products: Declarations of adverse reactions in the year 2009

被引:5
作者
Muentener, C. R. [1 ,2 ]
Bruckner, L. [3 ,4 ]
Stuerer, A.
Althaus, F. R. [1 ]
Caduff-Janosa, P. [2 ]
机构
[1] Univ Zurich, Inst Vet Pharmakol & Toxikol, CH-8057 Zurich, Switzerland
[2] Swissmedic, Schweizer Heilmittelinst, Bern, Switzerland
[3] IVI, Mittelhausern, Switzerland
[4] STIZ, Zurich, Switzerland
来源
SCHWEIZER ARCHIV FUR TIERHEILKUNDE | 2010年 / 152卷 / 12期
关键词
pharmacovigilance; antiparasitics; antiinfectives; vaccinovigilance; blue tongue disease; IVERMECTIN TOXICOSIS; AMITRAZ; TOXICITY;
D O I
10.1024/0036-7281/a000127
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
During the year 2009, 134 reports of suspected adverse drug reactions (ADRs) to veterinary medicinal products (VMPs) were received (106 in the year 2008). The distribution according to species and drug classes remained in line with previous years. Companion animals were involved in most of the reports (46% dogs, 19% cats), followed by cattle or calves (22 %). Antiparasitic drugs made the biggest part with 30% of the reports, followed by antiinfectives (19%) and hormones (13 %). Some reactions following their use are specifically discussed. 95 additional enquiries about ADRs of VMPs were received by the Swiss Toxicological Information Centre in Zurich. Most of them concerned dogs or cats and antiparasitics or anti-inflammatory drugs. In the vaccinovigilance program, a total of 1020 reports were received, of which 1000 were related to the vaccination against blue tongue disease. The most frequently reported adverse reactions were aborts, mastitis or alterations of milk quality and they are specifically discussed.
引用
收藏
页码:575 / 583
页数:9
相关论文
共 23 条
  • [1] Interaction of formamidine pesticides with the presynaptic α2-adrenoceptor regulating [3H]noradrenaline release from rat hypothalamic synaptosomes
    Altobelli, D
    Martire, M
    Maurizi, S
    Preziosi, P
    [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 2001, 172 (03) : 179 - 185
  • [2] [Anonymous], EPARS AUTH MED PROD
  • [3] CLARK CH, 1977, MOD VET PRACT, V58, P594
  • [4] DEMUTH D, 2010, TIERARZNEIMITTELKOMP
  • [5] Adverse drug reactions: definitions, diagnosis, and management
    Edwards, IR
    Aronson, JK
    [J]. LANCET, 2000, 356 (9237) : 1255 - 1259
  • [6] Near-fatal amitraz intoxication: The overlooked pesticide
    Elinav, E
    Shapira, Y
    Ofran, Y
    Hassin, T
    Ben-Dov, IZ
    [J]. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2005, 97 (03) : 185 - 187
  • [7] Retinopathy associated with ivermectin toxicosis in two dogs
    Kenny, Patrick J.
    Vernau, Karen M.
    Puschner, Birgit
    Maggs, David J.
    [J]. JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 2008, 233 (02): : 279 - 284
  • [8] KETRING KL, 1989, P 13 KAL KAN ANN S O, P109
  • [9] KROKER R, 2010, LEHRBUCH PHARM TOXIK, P444
  • [10] MCEVOY GK, 2007, AHFS DRUG INFORM, P208