Palladium-catalyzed enantioselective conjugate addition of arylboronic acids

被引：140

作者：

Gini, F ^{[1
]}

Hessen, B ^{[1
]}

Minnaard, AJ ^{[1
]}

机构：

[1] Univ Groningen, Stratingh Inst, Dept Organ Chem & Mol Inorgan Chem, NL-9747 AG Groningen, Netherlands

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 23期

关键词：

D O I：

10.1021/ol052222d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first asymmetric palladium-catalyzed conjugate addition of arylboronic acids to alpha,beta-unsaturated aldehydes, ketones, and esters is described. For cyclic substrates, excellent chemo-, regio-, and enantioselectivities are achieved when a Pd(O2CCF3)(2)/DuPHOS catalyst is applied.

引用

页码：5309 / 5312

页数：4

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