Determination of Methanol in Cosmetics by Headspace and Multidimensional Gas Chromatography with Mass Spectrometric Detection

被引：0

作者：

Yi, Xionghai ^{[1
]}

Guo, Dehua ^{[1
]}

Deng, Xiaojun ^{[1
]}

Li, Bo ^{[1
]}

Fan, Xiang ^{[1
]}

Zhu, Jian ^{[1
]}

机构：

[1] Shanghai Exit & Entry Inspect & Quarantine Bur, Tech Ctr Food Anim & Plant Inspect & Quarantine, Shanghai 201135, Peoples R China

来源：

JOURNAL OF AOAC INTERNATIONAL | 2011年 / 94卷 / 02期

关键词：

ESTER CONTENT; PECTINS; METHYLATION; FORMATE;

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel, reliable, and robust analytical method using headspace and multidimensional GC coupled to MS was successfully developed for determining the methanol content in cosmetics. The methanol was quantitatively analyzed and confirmed by heart-cutting multidimensional GC and mass selective detection in full scan mode. The average recovery was 99.8% with an RSD of 4.3%; the LOQ was 5 mg/kg. The proposed method showed good accuracy and precision while minimizing erroneous results due to false positives compared with conventional single-column GC analysis.

引用

页码：655 / 659

页数：5