Treatment of Sepsis in the Surgical Intensive Care Unit

被引:0
作者
Carney, Daniel E. [2 ]
Matsushima, Kazuhide [1 ]
Frankel, Heidi L. [3 ]
机构
[1] Penn State Milton S Hershey Med Ctr, Div Trauma Acute Care & Crit Care Surg, Hershey, PA 17033 USA
[2] Wellspan Hlth, York, PA USA
[3] Univ Maryland, Shock Trauma Ctr, Baltimore, MD 21201 USA
来源
ISRAEL MEDICAL ASSOCIATION JOURNAL | 2011年 / 13卷 / 11期
关键词
sepsis; intensive care unit (ICU); glucose control; steroids; parenteral nutrition; ACTIVATED PROTEIN-C; CRITICALLY-ILL; PARENTERAL-NUTRITION; INSULIN THERAPY; STRESS HYPERGLYCEMIA; CAMPAIGN GUIDELINES; ENTERAL NUTRITION; GLYCEMIC CONTROL; GLUCOSE CONTROL; SEPTIC SHOCK;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Since the Surviving Sepsis Campaign Guidelines (SSG) were published in 2004, critical care physicians can readily access the evidence and current recommendations regarding management of patients with severe sepsis and septic shock. However, several issues including a potential conflict of interest in developing the guidelines were disclosed. There have also been dramatic changes in the management of sepsis, supported by high levels of evidence. SSG 2008 was developed to update the evidence using a new grading system. We reviewed select topics, routinely addressed by intensivists in the surgical intensive care unit, that have changed between SSG 2004 and SSG 2008: namely, glucose control, and administration of steroids, recombinant human activated protein C (rhAPC) and total parenteral nutrition. IMAJ 2011; 13:694-699
引用
收藏
页码:694 / 699
页数:6
相关论文
共 37 条
[1]   Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death [J].
Abraham, E ;
Laterre, P ;
Garg, R ;
Levy, H ;
Talwar, D ;
Trzaskoma, BL ;
Francois, B ;
Guy, JS ;
Bruckmann, M ;
Rea-Neto, A ;
Rossaint, R ;
Perrotin, D ;
Sablotzki, A ;
Arkins, N ;
Utterback, BG ;
Macias, WL .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (13) :1332-1341
[2]   Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care [J].
Angus, DC ;
Linde-Zwirble, WT ;
Lidicker, J ;
Clermont, G ;
Carcillo, J ;
Pinsky, MR .
CRITICAL CARE MEDICINE, 2001, 29 (07) :1303-1310
[3]   Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock [J].
Annane, D ;
Sébille, V ;
Charpentier, C ;
Bollaert, PE ;
François, B ;
Korach, JM ;
Capellier, G ;
Cohen, Y ;
Azoulay, E ;
Troché, G ;
Chaumet-Riffaut, P ;
Bellissant, E .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 288 (07) :862-871
[4]  
[Anonymous], 2008, INTENS CARE MED, DOI [DOI 10.1007/s00134-007-0934-2, DOI 10.1007/s00134-008-1040-9]
[5]   Benefit/risk profile of drotrecogin alfa (activated) in surgical patients with severe sepsis [J].
Barie, PS ;
Williams, MD ;
McCollam, JS ;
Bates, BM ;
Qualy, RL ;
Lowry, SF ;
Fry, DE .
AMERICAN JOURNAL OF SURGERY, 2004, 188 (03) :212-220
[6]  
Barkun J, 2003, CAN J SURG, V46, P468
[7]   Efficacy and safety of recombinant human activated protein C for severe sepsis. [J].
Bernard, GR ;
Vincent, JL ;
Laterre, P ;
LaRosa, SP ;
Dhainaut, JF ;
Lopez-Rodriguez, A ;
Steingrub, JS ;
Garber, GE ;
Helterbrand, JD ;
Ely, EW ;
Fisher, CJ .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (10) :699-709
[8]   Reversal of late septic shock with supraphysiologic doses of hydrocortisone [J].
Bollaert, PE ;
Charpentier, C ;
Levy, B ;
Debouverie, M ;
Audibert, G ;
Larcan, A .
CRITICAL CARE MEDICINE, 1998, 26 (04) :645-650
[9]   A CONTROLLED CLINICAL-TRIAL OF HIGH-DOSE METHYLPREDNISOLONE IN THE TREATMENT OF SEVERE SEPSIS AND SEPTIC SHOCK [J].
BONE, RC ;
FISHER, CJ ;
CLEMMER, TP ;
SLOTMAN, GJ ;
METZ, CA ;
BALK, RA .
NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (11) :653-658
[10]   Intensive insulin therapy and pentastarch resuscitation in severe sepsis [J].
Brunkhorst, Frank M. ;
Engel, Christoph ;
Bloos, Frank ;
Meier-Hellmann, Andreas ;
Ragaller, Max ;
Weiler, Norbert ;
Moerer, Onnen ;
Gruendling, Matthias ;
Oppert, Michael ;
Grond, Stefan ;
Olthoff, Derk ;
Jaschinski, Ulrich ;
John, Stefan ;
Rossaint, Rolf ;
Welte, Tobias ;
Schaefer, Martin ;
Kern, Peter ;
Kuhnt, Evelyn ;
Kiehntopf, Michael ;
Hartog, Christiane ;
Natanson, Charles ;
Loeffler, Markus ;
Reinhart, Konrad .
NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (02) :125-139