Discovery of an Ebolavirus-Like Filovirus in Europe

被引：287

作者：

Negredo, Ana ^{[1
]}

Palacios, Gustavo ^{[2
,3
]}

Vazquez-Moron, Sonia ^{[1
]}

Gonzalez, Felix ^{[4
]}

Dopazo, Hernan ^{[5
]}

Molero, Francisca ^{[1
]}

Juste, Javier ^{[6
]}

Quetglas, Juan ^{[6
]}

Savji, Nazir ^{[2
,3
]}

de la Cruz Martinez, Maria ^{[1
]}

Herrera, Jesus Enrique ^{[2
,3
]}

Pizarro, Manuel ^{[7
]}

Hutchison, Stephen K. ^{[8
]}

Echevarria, Juan E. ^{[1
]}

Lipkin, W. Ian ^{[2
,3
]}

Tenorio, Antonio ^{[1
]}

机构：

[1] ISCIII, Natl Ctr Microbiol, Madrid, Spain

[2] Columbia Univ, Ctr Infect & Immun, New York, NY USA

[3] Columbia Univ, WHO Collaborating Ctr Diagnost Surveillance & Imm, Mailman Sch Publ Hlth, New York, NY USA

[4] Grp Asturiano Estudio & Conservac Murcielagos, Posada De Llanera, Principado De A, Spain

[5] Ctr Invest Principe Felipe, Evolutionary Genom Lab, Valencia, Spain

[6] CSIC, Estn Biol Donana, Evolutionary Biol Unit, E-41080 Seville, Spain

[7] Univ Complutense, Serv Pathol, Vet Teaching Hosp, Sch Vet, E-28040 Madrid, Spain

[8] Roche Life Sci, Branford, CT USA

来源：

PLOS PATHOGENS | 2011年 / 7卷 / 10期

关键词：

MARBURG VIRUSES; GLYCOPROTEIN; BAT; REEMERGENCE; RESERVOIR; PEPTIDE; DISEASE; RNA;

D O I：

10.1371/journal.ppat.1002304

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Filoviruses, amongst the most lethal of primate pathogens, have only been reported as natural infections in sub-Saharan Africa and the Philippines. Infections of bats with the ebolaviruses and marburgviruses do not appear to be associated with disease. Here we report identification in dead insectivorous bats of a genetically distinct filovirus, provisionally named Lloviu virus, after the site of detection, Cueva del Lloviu, in Spain.

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