Can anti-erosion dentifrices also provide effective plaque control?

被引:9
作者
Bellamy, P. G. [1 ]
Prendergast, M. [1 ]
Strand, R. [1 ]
Yu, Z. [2 ]
Day, T. N. [1 ]
Barker, M. L. [3 ]
Mussett, A. J. [1 ]
机构
[1] Procter & Gamble Co, London Innovat Ctr, Surrey, England
[2] Procter & Gamble Co, Beijing Tech Ctr, Beijing, Peoples R China
[3] Procter & Gamble Co, Mason Business Ctr, Mason, OH USA
关键词
clinical trial; dental hygiene; dentifrice/gel; fluoride; oral hygiene; plaque control; plaque formation; TITANIUM TETRAFLUORIDE; STANNOUS FLUORIDE; SODIUM-FLUORIDE; TISSUE-LOSS; IN-VITRO; ENAMEL; TOOTHPASTE;
D O I
10.1111/j.1601-5037.2010.00480.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Objective: While gingivitis and caries continue to be prevalent issues, there is growing concern about dental erosion induced by dietary acids. An oral hygiene product that protects against all these conditions would be beneficial. This study investigated the potential of two anti-erosion dentifrices to inhibit plaque. Methods: This was a randomized, three-period, two-treatment, double-blind, crossover study evaluating a stannous chloride/sodium fluoride dentifrice (SnCl2/NaF, blend-a-med (R) Pro Expert) and a popular anti-erosion dentifrice (NaF, Sensodyne (R) ProNamel (TM)). During Period 3, subjects were randomized to repeat one treatment to evaluate any product carryover effects. Each treatment period was 17 days. Test dentifrices were used with a standard manual toothbrush. Digital plaque image analysis (DPIA) was employed at the end of each period to evaluate plaque levels (i) overnight (AM prebrush); (ii) post-brushing with the test product (AM post-brush); and (iii) mid-afternoon (PM). Analysis was conducted via an objective computer algorithm, which calculated total area of visible plaque. Results: Twenty-seven subjects completed the study. At all time points, subjects had statistically significantly (P <= 0.0001) lower plaque levels after using the SnCl2/NaF dentifrice than the NaF dentifrice. The antiplaque benefit for the SnCl2/NaF dentifrice versus the NaF dentifrice was: AM prebrush = 26.0%; AM post-brushing = 27.9%; PM = 25.7%. Conclusions: The SnCl2/NaF dentifrice provided significantly greater daytime and overnight plaque inhibition than the NaF toothpaste. When recommending dentifrice to patients susceptible to dental erosion, clinicians can consider one that also inhibits plaque.
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页码:223 / 228
页数:6
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