PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping data

被引:327
作者
Wigginton, JE [1 ]
Abecasis, GR [1 ]
机构
[1] Univ Michigan, Sch Publ Hlth, Dept Biostat, Ctr Stat Genet, Ann Arbor, MI 48103 USA
关键词
D O I
10.1093/bioinformatics/bti529
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We describe a tool that produces summary statistics and basic quality assessments for gene-mapping data, accommodating either pedigree or case-control datasets. Our tool can also produce graphic output in the PDF format.
引用
收藏
页码:3445 / 3447
页数:3
相关论文
共 15 条
[1]   A general test of association for quantitative traits in nuclear families [J].
Abecasis, GR ;
Cardon, LR ;
Cookson, WOC .
AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 66 (01) :279-292
[2]   Merlin-rapid analysis of dense genetic maps using sparse gene flow trees [J].
Abecasis, GR ;
Cherny, SS ;
Cookson, WO ;
Cardon, LR .
NATURE GENETICS, 2002, 30 (01) :97-101
[3]   GRR: graphical representation of relationship errors [J].
Abecasis, GR ;
Cherny, SS ;
Cookson, WOC ;
Cardon, LR .
BIOINFORMATICS, 2001, 17 (08) :742-743
[4]   Testing the robustness of the likelihood-ratio test in a variance-component quantitative-trait loci-mapping procedure [J].
Allison, DB ;
Neale, MC ;
Zannolli, R ;
Schork, NJ ;
Amos, CI ;
Blangero, J .
AMERICAN JOURNAL OF HUMAN GENETICS, 1999, 65 (02) :531-544
[5]  
ELSTON R, 2004, SAGE STAT ANAL GENET, pH60
[6]   PROGRAMS FOR PEDIGREE ANALYSIS - MENDEL, FISHER, AND DGENE [J].
LANGE, K ;
WEEKS, D ;
BOEHNKE, M .
GENETIC EPIDEMIOLOGY, 1988, 5 (06) :471-472
[7]  
LANGE K, 1987, AM J HUM GENET, V40, P250
[8]  
LATHROP GM, 1985, AM J HUM GENET, V37, P482
[9]   Mega2: data-handling for facilitating genetic linkage and association analyses [J].
Mukhopadhyay, N ;
Almasy, L ;
Schroeder, M ;
Mulvihill, WP ;
Weeks, DE .
BIOINFORMATICS, 2005, 21 (10) :2556-2557
[10]   PedCheck: A program for identification of genotype incompatibilities in linkage analysis [J].
O'Connell, JR ;
Weeks, DE .
AMERICAN JOURNAL OF HUMAN GENETICS, 1998, 63 (01) :259-266