Enabling design and synthesis of small molecule protein-protein antagonists

被引：0
|
作者：
Camacho, Carlos J. [1 ]
Koes, David [1 ]
Doemling, Alexander [2 ]
机构：
[1] Univ Pittsburgh, Dept Computat & Syst Biol, Pittsburgh, PA 15261 USA
[2] Univ Pittsburgh, Sch Pharm, Pittsburgh, PA 15261 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 242卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
351-COMP
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Enabling Large-Scale Design, Synthesis and Validation of Small Molecule Protein-Protein Antagonists
    Koes, David
    Khoury, Kareem
    Huang, Yijun
    Wang, Wei
    Bista, Michal
    Popowicz, Grzegorz M.
    Wolf, Siglinde
    Holak, Tad A.
    Doemling, Alexander
    Camacho, Carlos J.
    PLOS ONE, 2012, 7 (03):
  • [2] Design and synthesis of small molecule ligands that mediate relevant protein-protein interactions.
    Minter, AR
    Mapp, AK
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 228 : U66 - U67
  • [3] Mimicking Intermolecular Interactions of Tight Protein-Protein Complexes for Small-Molecule Antagonists
    Xu, David
    Bum-Erdene, Khuchtumur
    Si, Yubing
    Zhou, Donghui
    Ghozayel, Mona K.
    Meroueh, Samy O.
    CHEMMEDCHEM, 2017, 12 (21) : 1794 - 1809
  • [4] Small Molecule Antagonists of the DNA Repair ERCC1/XPA Protein-Protein Interaction
    Obermann, Robert
    Yemane, Bereket
    Jarvis, Cassie
    Franco, Francisco M.
    Kyriukha, Yevhenii
    Nolan, William
    Gohara, Beth
    Krezel, Andrzej M.
    Wildman, Scott A.
    Janetka, James W.
    CHEMMEDCHEM, 2024, 19 (08)
  • [5] Small molecule inhibition of protein-protein interaction: An emerging paradigm in drug design
    Lindsley, Craig W.
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2007, 7 (10) : 921 - 921
  • [6] Small molecule modulation of transient protein-protein interactions
    Mapp, Anna K.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [7] Small molecule inhibitors of the XIAP protein-protein interaction
    Rajapakse, Hemaka A.
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2007, 7 (10) : 966 - 971
  • [8] Small-molecule inhibitors of protein-protein interactions
    Berg, Thorsten
    CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2008, 11 (05) : 666 - 674
  • [9] Bioinformatics of Protein-Protein Interfaces and Small Molecule Effectors
    Walter, Peter
    Ulucan, Ozlem
    Metzger, Jennifer
    Helms, Volkhard
    CURRENT BIOINFORMATICS, 2012, 7 (02) : 159 - 172
  • [10] Fragment hopping protocol for the design of small-molecule protein-protein interaction inhibitors
    Kell, Shelby R.
    Wang, Zhen
    Ji, Haitao
    BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 69
12345