Metal ion-binding properties of DNA duplexes containing thiopyrimidine base pairs

被引:46
|
作者
Okamoto, Itaru [1 ]
Ono, Takashi [1 ]
Sameshima, Rimi [1 ]
Ono, Akira [1 ]
机构
[1] Kanagawa Univ, Fac Engn, Dept Mat & Life Chem, Kanagawa Ku, Yokohama, Kanagawa 2218686, Japan
关键词
NUCLEOSIDES; OLIGONUCLEOTIDE; COORDINATION; COMPLEXES; SILVER(I);
D O I
10.1039/c2cc15436f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Thiopyrimidine pairs in DNA duplexes were unexpectedly largely stabilized by complexation with two equivalents of Ag(I) ions and their binding properties were evaluated. The metal ion-binding properties of the thiopyrimidine base pairs differed significantly from those of unpaired bases.
引用
收藏
页码:4347 / 4349
页数:3
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