Increasing incidence of late-onset anti-AChR antibody seropositive myasthenia gravis

被引:86
作者
Somnier, FE [1 ]
机构
[1] Statens Serum Inst, Dept Autoimmunol, DK-2300 Copenhagen, Denmark
关键词
D O I
10.1212/01.wnl.0000176067.32186.a3
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The incidence of myasthenia gravis (MG) from 1970 through 1999 was studied in an area with 2.3 million inhabitants. The mean annual incidence rate of early-onset MG was constant at 3.5 x 10(-6). In late-onset MG, the rate increased from 4.7 to 20.8 x 10(-6). The two onset types of MG may thus be distinct disorders. The author hypothesized that late-onset nonthymoma anti-acetylcholine receptor antibody-seropositive MG may be provoked by environmental factors.
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页码:928 / 930
页数:3
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