Allogeneic stem cell transplantation with reduced intensity conditioning in lymphoproliferative disorders

被引:0
作者
Vigouroux, S. [1 ]
机构
[1] CHU Bordeaux, Hop Haut Leveque, Serv Malad Sang, F-33600 Pessac, France
关键词
Reduced-conditioning allogeneic stem cell transplantation; Multiple myeloma; Follicular lymphoma; Diffuse large B-cell lymphoma; Peripheral T-cell lymphoma; TERM-FOLLOW-UP; ADVANCED FOLLICULAR LYMPHOMA; BONE-MARROW-TRANSPLANTATION; NEWLY-DIAGNOSED MYELOMA; NOVO MULTIPLE-MYELOMA; NON-HODGKINS-LYMPHOMA; LOW-GRADE LYMPHOMA; PERIPHERAL T-CELL; AUTOLOGOUS TRANSPLANTATION; EUROPEAN GROUP;
D O I
10.1007/s10269-011-2064-2
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The role of reducedintensity allogeneic stem cell transplantation in lymphoid hematologic malignancies is not consensual and remains difficult to define mainly because of lack of comparative studies. In myeloma, the topic is extremely controversial in first-line therapy and in more advanced disease. It seems that the procedure might be beneficial in relapsed chemosensitive diffuse large B-cell lymphoma and in advanced follicular lymphoma. In peripheral T-cell lymphoma, the promising results in relapse have stimulated efforts to evaluate allogeneic transplants in first line. However, it is important to note that because of many uncertainties surrounding allogeneic stem cell transplantation in lymphoid malignancies, the best transplant strategy would be to include patients in clinical trials whenever possible. To cite this journal: Oncologie 13 (2011).
引用
收藏
页码:559 / 564
页数:6
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