Leishmanicidal alkaloids from Kopsia griffithii

被引：73

作者：

Kam, TS ^{[1
]}

Sim, KM

Koyano, T

Komiyama, K

机构：

[1] Univ Malaya, Dept Chem, Kuala Lumpur 50603, Malaysia

[2] Temko Corp, Tokyo 164, Japan

[3] Kitasato Inst, Minato Ku, Tokyo 108, Japan

来源：

PHYTOCHEMISTRY | 1999年 / 50卷 / 01期

关键词：

Kopsia griffithii; Apocynaceae; stem-bark; antileishmanial alkaloids;

D O I：

10.1016/S0031-9422(98)00492-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Thirteen alkaloids were isolated from the stem-bark extract of Kopsia griffithii, of which three were new. These were the N(4)-oxides of akuammiline, 16-epi-deacetylakuammiline and 11,12-methylenedioxykopsinaline. Harmane, pleiocarpine and buchtienine showed antileishmanial activity. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：75 / 79

页数：5

共 20 条

[1]

ABE F, 1994, PHYTOCHEMISTRY, V35, P169, DOI 10.1016/S0031-9422(00)90527-2

[2]

ALLEY MC, 1988, CANCER RES, V48, P589

[3] LAPIDILECTINE-A AND LAPIDILECTINE-B, 2 NEW ALKALOIDS FROM KOPSIA-LAPIDILECTA [J].