GnRH agonist for triggering final oocyte maturation in patients at risk of ovarian hyperstimulation syndrome: still a controversy?

被引：23

作者：

Kol, S. ^{[1
,2
]}

Solt, I. ^{[1
,3
]}

机构：

[1] Women Hlth Ctr, Maccabi Hlth Serv, Haifa, Israel

[2] Rambam Med Ctr, IVF Unit, Haifa, Israel

[3] Western Galilee Hosp, Nahariyya, Israel

来源：

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS | 2008年 / 25卷 / 2-3期

关键词：

GnRH agonist; luteal support; OHSS; ovulation; prevention;

D O I：

10.1007/s10815-008-9198-1

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Purpose An update on the subject of ovarian hyperstimulation syndrome (OHSS) prevention with GnRH agonist ovulation trigger. Methoods Review of pertinent English language studies published during the past 4 years. Results Randomized prospective studies support the notion that agonist trigger completely eliminates OHSS. Conflicting results regarding on going pregnancy rate probably reflect different approaches to luteal phase support. Embryos obtained and frozen after agonist trigger yield good clinical outcome in subsequent thaw cycles. Conclusions The notion that agonist trigger can eliminate OHSS is strongly supported by randomized controlled trials. Further research is needed to assess optimal luteal support post agonist trigger.

引用

页码：63 / 66

页数：4

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