Evaluation of anti-malarial effects of mass chemoprophylaxis in the Republic of Korea Army

被引：29

作者：

Yeom, JS

Ryu, SH

Oh, S

Choi, DH

Song, KJ

Oh, YH

Lee, JH

Kim, YA

Ahn, SY

Yang, HY

Cha, JE

Park, JW

机构：

[1] Gachon Med Sch, Dept Microbiol, Inchon 405760, South Korea

[2] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Sch Med, Dept Internal Med, Seoul, South Korea

[3] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Sch Med, Dept Occupat Med, Seoul, South Korea

[4] Daegu Hosp, Korea Armed Forces, Taegu, South Korea

[5] Kyung Hee Univ, Coll Med, Dept Surg, Seoul, South Korea

[6] Seoul Natl Univ, Coll Med, Dept Emergency Med, Seoul, South Korea

[7] Hanyang Univ, Coll Med, Dept Pathol, Seoul 133791, South Korea

来源：

JOURNAL OF KOREAN MEDICAL SCIENCE | 2005年 / 20卷 / 05期

关键词：

malaria; vivax; Korea; chemoprevention; chloroquine; primaquine;

D O I：

10.3346/jkms.2005.20.5.707

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Vivax malaria was endemic on the Korean peninsula for many centuries until the late 1970's when the Republic of Korea (ROK) was declared "malaria free". Since its re-emergence in 1993, the number of malaria cases in the military increased exponentially through 2000 near the demilitarized zone. Chemoprophylaxis with chloroquine and primaquine has been used in the ROK Army since 1997 in an attempt to reduce the number of the malaria cases throughout the ROK. Data show that chemoprophylaxis contributed, in part, to the decrease in the number of malaria cases among militant personnel. However, mass chemoprophylaxis on a large scale in the ROK Army is unprecedented and extensive supervision and monitoring is warranted to determine its effectiveness and to monitor the appearance of chloroquine tolerant/resistant strains of Plasmodium vivax.

引用

页码：707 / 712

页数：6

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