RETRACTED: Fluorescent sensing study and prevention ability on Alzheimer's disease by reducing the oxidative stress injury in the nerve cells of two Zn(II) coordination polymers (Retracted article. See vol. 320, 2023)

By using terphenyl-3,3 '',5,5 ''-tetracarboxylic acid (H(4)tptc) ligand and different N-donor co-ligands, two Zn(II)-based coordination polymers (CPs) {[Zn(tptc)(1,2-bimb)(2) ]center dot 4.5(H2O)}(n)(1, 1,2-bimb = 1,2-bis (imidazol-1-ylmethyl) benzene) and {[Zn-3(Htptc)(2)(2,2'-bpy)(2)]center dot 1.5H(2)O}(n) (2, 2,2'-bpy = 2,2'-bipyridine) were prepared. Compound 1 could be used as a sensor for Fe3+ ion with a low detection limit. To develop novel candidates for Alzheimer's disease (AD) treatment, ELISA detection kit was used to determine the A beta 40 and A beta 42 content produced in nerve cells. RT-PCR was carried out to measure the ROS related genes relative expression levels, for example, pg91 and gp21.