Body mass index is not associated with early onset cataract in the 45 and Up cohort study

被引：5

作者：

Zhang, Jiaqing ^{[1
]}

Wang, Wei ^{[1
]}

Yang, Guangyao ^{[2
]}

Ha, Jason ^{[3
]}

Tan, Xuhua ^{[1
]}

Shang, Xianwen ^{[3
]}

Zhu, Zhuoting ^{[4
]}

Han, Xiaotong ^{[1
]}

Liu, Zhenzhen ^{[1
]}

Zhang, Lei ^{[3
,5
,6
,7
]}

He, Mingguang ^{[1
,3
,8
]}

Luo, Lixia ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Natl Clin Res Ctr, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, Guangzhou, Peoples R China

[2] Municipal Hosp Chifeng, Dept Ophthalmol, Chifeng, Inner Mongolia, Peoples R China

[3] Royal Victorian Eye & Ear Hosp, Ctr Eye Res Australia, Melbourne, Vic, Australia

[4] Guangdong Acad Med Sci, Guangdong Prov Peoples Hosp, Dept Ophthalmol, Guangzhou, Peoples R China

[5] Alfred Hlth, Melbourne Sexual Hlth Ctr, Artificial Intelligence & Modelling Epidemiol Pro, Melbourne, Vic, Australia

[6] Monash Univ, Fac Med, Cent Clin Sch, Melbourne, Vic, Australia

[7] Zhengzhou Univ, Coll Publ Hlth, Dept Epidemiol & Biostat, Zhengzhou, Peoples R China

[8] Univ Melbourne, Dept Surg, Ophthalmol, Melbourne, Vic, Australia

来源：

ANNALS OF TRANSLATIONAL MEDICINE | 2021年 / 9卷 / 22期

基金：

澳大利亚国家健康与医学研究理事会; 中国国家自然科学基金;

关键词：

Early-onset cataract; risk factor; Australian; 45 and Up Study; cohort; SELF-REPORTED HEIGHT; AGE-RELATED CATARACT; RISK-FACTORS; METABOLIC SYNDROME; LENS OPACITIES; POPULATION; EXTRACTION; OBESITY; WEIGHT; SURGERY;

D O I：

10.21037/atm-21-2775

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Body mass index (BMI) has been reported to be associated with age-related cataract, whereas its impact on early onset cataract (EOC) remains unknown. Methods: A total of 73,007 individuals aged 45-55 years who had no previous cataract surgeries at baseline were enrolled from the population-based 45 and Up Study. BMI was calculated based on self-reported height and weight from the baseline questionnaire. Data on cataract surgeries were obtained from the Medicare Benefits Schedule database. EOC was defined as cataract surgically treated prior to 65 years of age. A Cox proportional hazards regression was used to assess the association between BMI and the incidence of EOC during the follow-up. Results: A total of 1,764 participants underwent cataract surgery over 643,717 person-years of followup. No significant association was observed between BMI and EOC (P for trend 0.35). Among participants who drank 5 to 7 alcoholic drinks per week, a 73% and 27% reduction in the risk of EOC was observed in participants with a BMI of 18.5-19.99 kg/m(2) and 25.0-27.49 kg/m(2), respectively, compared to those with a BMI of 20.0-22.49 kg/m(2). Conclusions: No association was identified between BMI and the incidence of EOC. Moderate alcohol intake may be protective against EOC.

引用

页数：10

共 33 条

[31] A prospective study of the relationship between body mass index and cataract extraction among US women and men [J].