Rapid synthesis of nontoxic and photostable carbon nanoparticles for bioimaging applications

被引：22

作者：

Molkenova, Anara ^{[1
]}

Toleshova, Aidana ^{[1
]}

Song, Su-Jin ^{[2
]}

Kang, Moon Sung ^{[2
]}

Abduraimova, Aiganym ^{[1
]}

Han, Dong-Wook ^{[2
]}

Atabaev, Timur Sh ^{[1
]}

机构：

[1] Nazarbayev Univ, Dept Chem, Nur Sultan 010000, Kazakhstan

[2] Pusan Natl Univ, Dept Cognomechatron Engn, Busan 46241, South Korea

来源：

MATERIALS LETTERS | 2020年 / 261卷

关键词：

Carbon materials; Nanoparticles; Fluorescence; Photostability; Cytotoxicity; Bioimaging; ONE-STEP SYNTHESIS; DOTS; NANODOTS;

D O I：

10.1016/j.matlet.2019.127012

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

In this study, fluorescent carbon nanoparticles (CNPs) with quantum yield of 6.08% have been synthesized using a hydrothermal method within a short period of time (t = 30 min). Fluorescence spectroscopy (FS) revealed that CNPs demonstrate excellent photostability which is suitable for prolonged bioimaging applications. Cytotoxicity study with L-929 fibroblastic cells showed that prepared CNPs are nontoxic even at relatively high concentrations up to 250 mu g/ml. Strong green fluorescence signal observed from L-929 cells suggested that CNPs can be utilized for in-vitro tissues/cells bioimaging applications. (C) 2019 Elsevier B.V. All rights reserved.

引用

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