A psoriasis-like cutaneous inflammation in K14/VEGF-transgenic mice is characterised by epidermal hyperplasia and pronounced infiltration of T-cells in the skin

被引:0
|
作者
Hvid, Henning [1 ]
Svensson, L. [1 ]
Kvist, P. H. [1 ]
Kemp, K. [1 ]
Petersen, T. K. [1 ]
机构
[1] LEO Pharma, Ballerup, Denmark
关键词
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:S437 / S438
页数:2
相关论文
共 15 条
  • [1] Calcipotriol inhibits psoriasis-like angiogenic features in K14-VEGF transgenic mice
    Cao, Mengke
    Mei, Lihong
    Xiao, Ming
    Li, Jing
    Fang, Fang
    EUROPEAN JOURNAL OF DERMATOLOGY, 2022, 32 (01) : 24 - 33
  • [2] Calcipotriol inhibits psoriasis-like angiogenic features in K14-VEGF transgenic mice
    Mengke Cao
    Lihong Mei
    Ming Xiao
    Jing Li
    Fang Fang
    European Journal of Dermatology, 2022, 32 : 24 - 33
  • [3] Psoriasis-like inflammation in K14PPARβ/δ transgenic mice selectively overexpressing PPARβ/δ in keratinocytes
    Dezoteux, F.
    Quemener, S.
    Fleury, S.
    Lefebvre, P.
    Staels, B.
    Dombrowicz, D.
    Gross, B.
    Staumont-Salle, D.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2017, 137 (10) : S256 - S256
  • [4] TPA induction leads to a Th17-like response in transgenic K14/VEGF mice:: A novel in vivo screening model of psoriasis
    Hvid, Henning
    Teige, Ingrid
    Kvist, Peter Helding
    Svensson, Lars
    Kemp, Kare
    INTERNATIONAL IMMUNOLOGY, 2008, 20 (08) : 1097 - 1106
  • [5] HMGB1 Inhibitor Effectively Alleviates Psoriasis-Like Lesions and Inflammatory Cytokines in K14-VEGF Transgenic Mice
    Fu Li-Xin
    Yin Bin
    Cao Na
    Qin Sha
    Lei Xiao-Yu
    Chen Tao
    Guo Zai-Pei
    国际皮肤性病学杂志(英文), 2023, 06 (01)
  • [6] Systemic ALA-PDT effectively blocks the development of psoriasis-like lesions and alleviates leucocyte infiltration in the K14-VEGF transgenic mouse
    Chen, T.
    Zhang, L. -W.
    Fu, L. -X.
    Wu, Y. -B.
    Liu, X. -Y.
    Guo, Z. -P.
    CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2017, 42 (08) : 849 - 856
  • [7] Human β-Defensin 3 and Its Mouse Ortholog Murine β-Defensin 14 Activate Langerhans Cells and Exacerbate Psoriasis-Like Skin Inflammation in Mice
    Sweeney, Cheryl M.
    Russell, Shane E.
    Malara, Anna
    Kelly, Genevieve
    Hughes, Rosalind
    Tobin, Anne-Marie
    Adamzik, Karoline
    Walsh, Patrick T.
    Kirby, Brian
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2016, 136 (03) : 723 - 727
  • [8] Systemic VEGF inhibition decreases CD4+T cells and Th17 cytokines improving psoriasis-like skin inflammation in KC-Tie2 mice
    Diaconu, D.
    Fritz, Y.
    Dawes, S. M.
    Loyd, C. M.
    Ward, N. L.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2013, 133 : S39 - S39
  • [9] VEGF-Trap decreases CD4+ T cells, Th17 cytokines improving psoriasis-like skin inflammation in KC-Tie2 mice
    Diaconu, Doina
    Fritz, Yi
    Dawes, Sean M.
    Loyd, Candace M.
    Ward, Nicole L.
    JOURNAL OF DERMATOLOGICAL SCIENCE, 2013, 72 (03) : 322 - 325
  • [10] Keratinocyte-derived CCL20 orchestrates epidermal localization of IL-17-producing γδ T cells and ILCs to mediate psoriasis-like skin inflammation
    Singh, Tej Pratap
    Lu, Xinping
    Singh, Satya P.
    Zhang, Hongwei
    Doucet, Michele
    Kominsky, Scott L.
    Farber, Joshua M.
    JOURNAL OF IMMUNOLOGY, 2019, 202 (01)