Reaction between isocyanides and chalcones: an effcient solvent-free synthesis of 5-hydroxy-3,5-diaryl-1,5dihydro-2H-pyrrol-2-ones

被引：50
作者：
Adib, Mehdi [1 ]
Mahdavi, Mohammad [1 ]
Noghani, Mahsa Alizadeh [1 ]
Bijanzadeh, Hamid Reza [1 ]
机构：
[1] Univ Tehran, Univ Coll Sci, Sch Chem, Tehran, Iran
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 45期
关键词：
5-hydroxy-3,5-diaryl-1,5-dihydro-2H-pyrrol-2-ones; gamma-hydroxy-alpha-beta-unsaturated gamma-lactams; 1,3-diaryl-2-propen-1-ones; isocyanides; solvent-free synthesis;
D O I：
10.1016/j.tetlet.2007.09.030
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and efficient synthesis of 5-hydroxy-3,5-diaryl-1,5-dihydro-2H-pyrrol-2-ones is described. Heating a mixture of an isocyanide and a 1,3-diaryl-2-propen-1-one under solvent-free conditions produces the title compounds in good to excellent yields. (C) 2007 Elsevier Ltd. All rights reserved.
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收藏
页码：8056 / 8059
页数：4
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