The ecotoxicology of titanium dioxide nanoparticles, an important engineering nanomaterial

被引:19
作者
Du, Jia [1 ]
Xu, Shaodan [1 ]
Zhou, Qinwei [1 ]
Li, Huanxuan [1 ]
Fu, Li [1 ]
Tang, Jun-Hong [1 ]
Jin, Mei-Qing [1 ]
机构
[1] Hangzhou Dianzi Univ, Inst Environm Sci & Engn, Coll Mat & Environm Engn, 1158 Baiyang Rd, Hangzhou 310018, Peoples R China
关键词
Ecotoxicology; application; mechanism; titanium dioxide nanoparticles; SHORT-TERM EXPOSURE; IN-VITRO TOXICITY; TIO2; NANOPARTICLES; OXIDATIVE STRESS; DAPHNIA-MAGNA; REPRODUCTIVE TOXICITY; OXIDE NANOPARTICLES; GROWTH-INHIBITION; CARBON NANOTUBES; ORAL-EXPOSURE;
D O I
10.1080/02772248.2019.1693572
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Titanium dioxide nanoparticles (nano-TiO2) are useful because of their unique physicochemical properties. The wide application of nano-TiO2 has raised concerns regarding its potential threat to organisms and the environment. Therefore, the production and application of nano-TiO2 in the global market is summarized in this paper. This review presents the adverse effects of nano-TiO2 in vivo, including potential exposure routes such as transdermal, oral and inhalative exposure, risk evaluation of nanotoxicity in vitro using bacteria, microorganisms, cells and biological molecules), physicochemical characterization of nano-TiO2 regarding crystal structure, size, shape, surface characteristics and coatings, and the mechanisms of toxicity of nano-TiO2 based on environmentally relevant test species and cells. This review aims to fill deficiencies in toxicological research and to facilitate the assessment of the environmental risks by nano-TiO2 which is conducive to designing safer nanoproducts in our daily life.
引用
收藏
页码:165 / 189
页数:25
相关论文
共 102 条
[1]   In vivo effect of industrial titanium dioxide nanoparticles experimentally exposed to hairless rat skin [J].
Adachi, Koji ;
Yamada, Nanako ;
Yamamoto, Kazuhiro ;
Yoshida, Yuichi ;
Yamamoto, Osamu .
NANOTOXICOLOGY, 2010, 4 (03) :296-306
[2]   Comparative eco-toxicity of nanoscale TiO2, SiO2, and ZnO water suspensions [J].
Adams, Laura K. ;
Lyon, Delina Y. ;
Alvarez, Pedro J. J. .
WATER RESEARCH, 2006, 40 (19) :3527-3532
[3]  
Afaq F, 1998, J APPL TOXICOL, V18, P307, DOI 10.1002/(SICI)1099-1263(1998090)18:5<307::AID-JAT508>3.0.CO
[4]  
2-K
[5]   Short-term oral exposure to low doses of nano-sized TiO2 and potential modulatory effects on intestinal cells [J].
Ammendolia, Maria Grazia ;
Iosi, Francesca ;
Maranghi, Francesca ;
Tassinari, Roberta ;
Cubadda, Francesco ;
Aureli, Federica ;
Raggi, Andrea ;
Superti, Fabiana ;
Mantovani, Alberto ;
De Berardis, Barbara .
FOOD AND CHEMICAL TOXICOLOGY, 2017, 102 :63-75
[6]   Toxicity of nanoparticles of CuO, ZnO and TiO2 to microalgae Pseudokirchneriella subcapitata [J].
Aruoja, Villem ;
Dubourguier, Henri-Charles ;
Kasemets, Kaja ;
Kahru, Anne .
SCIENCE OF THE TOTAL ENVIRONMENT, 2009, 407 (04) :1461-1468
[7]   Intrinsic therapeutic applications of noble metal nanoparticles: past, present and future [J].
Arvizo, Rochelle R. ;
Bhattacharyya, Sanjib ;
Kudgus, Rachel A. ;
Giri, Karuna ;
Bhattacharya, Resham ;
Mukherjee, Priyabrata .
CHEMICAL SOCIETY REVIEWS, 2012, 41 (07) :2943-2970
[8]   Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles [J].
Bermudez, E ;
Mangum, JB ;
Wong, BA ;
Asgharian, B ;
Hext, PM ;
Warheit, DB ;
Everitt, JI .
TOXICOLOGICAL SCIENCES, 2004, 77 (02) :347-357
[9]   Aqueous Hg2+ associates with TiO2 nanoparticles according to particle size, changes particle agglomeration, and becomes less bioavailable to zebrafish [J].
Boran, Halis ;
Boyle, David ;
Altinok, Ilhan ;
Patsiou, Danae ;
Henry, Theodore B. .
AQUATIC TOXICOLOGY, 2016, 174 :242-246
[10]   Effects of nanoparticles in fresh waters: risks, mechanisms and interactions [J].
Bundschuh, Mirco ;
Seitz, Frank ;
Rosenfeldt, Ricki R. ;
Schulz, Ralf .
FRESHWATER BIOLOGY, 2016, 61 (12) :2185-2196