Insulin signaling: GLUT4 vesicles exit via the exocyst

被引:43
作者
Kanzaki, M [1 ]
Pessin, JE [1 ]
机构
[1] SUNY Stony Brook, Dept Pharmacol Sci, Stony Brook, NY 11794 USA
关键词
D O I
10.1016/S0960-9822(03)00478-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The localization of the GTP-binding protein TC10 to lipid raft microdomains has been suggested to play a role in the stimulation of GLUT4 translocation. The exocyst has now been identified as a downstream target for TC10, directing GLUT4-containing vesicles to the site of fusion.
引用
收藏
页码:R574 / R576
页数:3
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