Effects of biodegradable hydrogel spacer injection on contralateral submandibular gland sparing in radiotherapy for head and neck cancers

被引：12

作者：

Rao, Avani D. ^{[1
]}

Coquia, Stephanie ^{[2
]}

De Jong, Robert ^{[2
]}

Gourin, Christine ^{[3
]}

Page, Brandi ^{[1
]}

Latronico, Diane ^{[1
]}

Dah, Samson ^{[1
]}

Su, Lin ^{[1
]}

Clarke, Stephen ^{[1
]}

Schultz, Jeffrey ^{[1
]}

Rosati, Lauren M. ^{[1
]}

Fakhry, Carole ^{[3
]}

Wong, John ^{[1
]}

DeWeese, Theodore L. ^{[1
]}

Quon, Harry ^{[1
]}

Ding, Kai ^{[1
]}

Kiess, Ana ^{[1
]}

机构：

[1] Johns Hopkins Sch Med, Dept Radiat Oncol & Mol Radiat Sci, Baltimore, MD USA

[2] Johns Hopkins Sch Med, Dept Radiol, Baltimore, MD USA

[3] Johns Hopkins Sch Med, Dept Otolaryngol Head & Neck Surg, Baltimore, MD USA

来源：

RADIOTHERAPY AND ONCOLOGY | 2018年 / 126卷 / 01期

关键词：

Submandibular gland; Xerostomia; Radiation therapy; INTENSITY-MODULATED RADIOTHERAPY; RADIATION-THERAPY; SALIVARY-GLANDS; INDUCED XEROSTOMIA; FLOW-RATES; IMRT; VOLUME; LIFE;

D O I：

10.1016/j.radonc.2017.09.017

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Xerostomia is the most common late toxicity after head and neck radiation. We demonstrate injection of a hydrogel spacer anteriorly displacing the submandibular gland. This procedure enables reduced dose to the displaced submandibular gland in cadaveric models of oropharynx cancer treated with IMRT, with potential implications in reducing xerostomia risk. (C) 2017 The Author(s). Published by Elsevier Ireland Ltd.

引用

页码：96 / 99

页数：4

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