Current Trends and New Frontiers in Focal Therapy for Localized Prostate Cancer

被引:11
作者
Mendez, Melissa H. [1 ]
Joh, Daniel Y. [2 ]
Gupta, Rajan [3 ]
Polascik, Thomas J. [1 ]
机构
[1] Duke Univ, Med Ctr, Duke Canc Inst, Durham, NC 27710 USA
[2] Duke Univ, Dept Biomed Engn, Durham, NC 27710 USA
[3] Duke Univ, Med Ctr, Dept Radiol, Durham, NC 27710 USA
关键词
Prostate cancer; Focal therapy; Multiparametric MRI; PI-RADS; Cryotherapy; High-intensity-focused ultrasound; INTENSITY FOCUSED ULTRASOUND; APPARENT DIFFUSION-COEFFICIENT; RESONANCE-IMAGING MRI; CONTRAST-ENHANCED MRI; RADICAL PROSTATECTOMY; ACTIVE SURVEILLANCE; LOW-RISK; T; MULTIPARAMETRIC MRI; ONCOLOGIC OUTCOMES;
D O I
10.1007/s11934-015-0513-y
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Prostate cancer (PCa) care is an ever-evolving field. Research and technological developments continue to refine our definitions and management of this disease. Now, with a greater understanding of the natural history of PCa, the prevention of overtreatment has shaped a new era with the adoption of active surveillance (AS) and advancement of focal therapy (FT). Multiparametric magnetic resonance imaging (mpMRI) allows us to define, locate, and monitor cancers in a way never before possible. These capabilities combined with promising results from current prospective studies have changed the face of FT. This review presents the latest developments, current trends, and next steps in FT.
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页数:11
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