Studies on cantilever based triglyceride biosensor

被引:2
作者
Fernandez, Renny Edwin [1 ]
Soma, Sekhar B. V. [2 ]
Bhattacharya, Enakshi [1 ]
Chadha, Anju [3 ]
机构
[1] Indian Inst Technol, Dept Elect Engn, Microelect & MEMS Lab, Madras 600036, Tamil Nadu, India
[2] Indian Inst Technol, Ctr Nondestruct Evaluat, Dept Mech Engn, Madras, Tamil Nadu, India
[3] Indian Inst Technol, Natl Ctr Catalysis Res, Dept Biotechnol, Madras 600036, Tamil Nadu, India
来源
PROCEEDINGS OF THE 2007 INTERNATIONAL WORKSHOP ON THE PHYSICS OF SEMICONDUCTOR DEVICES: IWPSD-2007 | 2007年
关键词
biosensor; microcantilever; resonance frequency; triglyceride; vibrometer;
D O I
10.1109/IWPSD.2007.4472613
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
We report detection of micromolar levels of triglycerides using surface micromachined polysilicon cantilever beams. Enzymatic hydrolysis of triglycerides produces glycerol which alters the viscosity and density of the solution. This affects the dynamic properties of cantilever beams immersed in the solution. The change in the resonance frequency of the cantilever beams in the solution is measured using Doppler Vibrometry and the concentration of triglyceride is determined by comparing with a predetermined calibration plot.
引用
收藏
页码:690 / +
页数:2
相关论文
共 8 条
[1]   Solid state potentiometric sensor for the estimation of tributyrin and urea [J].
Basu, I ;
Subramanian, RV ;
Mathew, A ;
Kayastha, AM ;
Chadha, A ;
Bhattacharya, E .
SENSORS AND ACTUATORS B-CHEMICAL, 2005, 107 (01) :418-423
[2]  
BHAT S, 2007, IN PRESS J MICRO NAN
[3]   Detection of pathogen Escherichia coli O157:H7 using self-excited PZT-glass microcantilevers [J].
Campbell, GA ;
Mutharasan, R .
BIOSENSORS & BIOELECTRONICS, 2005, 21 (03) :462-473
[4]   Glucose biosensor based on the microcantilever [J].
Pei, JH ;
Tian, F ;
Thundat, T .
ANALYTICAL CHEMISTRY, 2004, 76 (02) :292-297
[5]   The pH-detection of triglycerides [J].
Pijanowska, DG ;
Baraniecka, A ;
Wiater, R ;
Ginalska, G ;
Lobarzewski, J ;
Torbicz, W .
SENSORS AND ACTUATORS B-CHEMICAL, 2001, 78 (1-3) :263-266
[6]   Micromechanical cantilever-based biosensors [J].
Raiteri, R ;
Grattarola, M ;
Butt, HJ ;
Skládal, P .
SENSORS AND ACTUATORS B-CHEMICAL, 2001, 79 (2-3) :115-126
[7]   Chemical sensors and biosensors in liquid environment based on microcantilevers with amplified quality factor [J].
Tamayo, J ;
Humphris, ADL ;
Malloy, AM ;
Miles, MJ .
ULTRAMICROSCOPY, 2001, 86 (1-2) :167-173
[8]   Resonant frequencies of a rectangular cantilever beam immersed in a fluid [J].
Van Eysden, Cornelis A. ;
Sader, John E. .
JOURNAL OF APPLIED PHYSICS, 2006, 100 (11)