Adhesion of biocompatible and biodegradable micropatterned surfaces

被引：16
|
作者：
Kaiser, Jessica S. [2 ]
Kamperman, Marleen [1 ,2 ]
de Souza, Emerson J. [2 ,3 ]
Schick, Bernhard [4 ]
Arzt, Eduard [2 ]
机构：
[1] Wageningen Univ, Lab Phys Chem & Colloid Sci, NL-6703 HB Wageningen, Netherlands
[2] INM Leibniz Inst New Mat, Funct Surfaces Grp, Saarbrucken, Germany
[3] Univ Illinois, Urbana, IL 61801 USA
[4] Hosp Homburg, Dept Otorhinolaryngol, Homburg, Germany
来源：
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS | 2011年 / 34卷 / 02期
关键词：
Bioinspiration; Gecko adhesion; Tissue engineering; Biodegradability; Tympanic membrane restoration; GECKO; FORCE;
D O I：
10.5301/IJAO.2011.6393
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
We studied the effects of pillar dimensions and stiffness of biocompatible and biodegradable micropatterned surfaces on adhesion on different compliant substrates. The micropatterned adhesives were based on biocompatible polydimethylsiloxane (PDMS) and biodegradable poly(lactic-co-glycolic) acid (PLGA) polymer systems. Micropatterned and non-patterned compliant PDMS did not show significant differences in adhesion on compliant mice ear skin or on gelatin-glycerin model substrates. However, adhesion measurements for micropatterned stiff PLGA on compliant gelatin-glycerin model substrates showed significant enhancement in pull-off strengths compared to non-patterned controls.
引用
收藏
页码：180 / 184
页数：5
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