Xenograft-directed personalized therapy for a patient with post-transplant relapse of ALL

被引:5
作者
Trahair, T. N. [1 ,2 ,3 ]
Lock, R. B. [2 ,3 ]
Sutton, R. [2 ,3 ]
Sia, K. C. S. [2 ,3 ]
Evans, K. [2 ]
Richmond, J. [2 ]
Law, T. [2 ]
Venn, N. C. [2 ]
Irving, J. A. [4 ]
Moore, S. [5 ]
Nievergall, E. [6 ,7 ]
Dang, P. [6 ]
Heatley, S. L. [6 ,7 ]
White, D. L. [6 ,7 ,8 ]
Revesz, T. [8 ,9 ]
机构
[1] Sydney Childrens Hosp, Kids Canc Ctr, High St, Randwick, NSW, Australia
[2] UNSW Australia, Lowy Canc Res Ctr, Childrens Canc Inst, Sydney, NSW, Australia
[3] UNSW Australia, Sch Womens & Childrens Hlth, Sydney, NSW, Australia
[4] Newcastle Univ, Northern Inst Canc Res, Newcastle Upon Tyne, Tyne & Wear, England
[5] SA Pathol, Dept Genet Pathol, Adelaide, SA, Australia
[6] SAHMRI, Adelaide, SA, Australia
[7] Univ Adelaide, Discipline Med, Adelaide, SA, Australia
[8] Univ Adelaide, Discipline Paediat, Adelaide, SA, Australia
[9] Womens & Childrens Hosp, SA Pathol, Adelaide, SA, Australia
关键词
ACUTE LYMPHOBLASTIC-LEUKEMIA; PRECLINICAL TESTING PROGRAM; 1ST RELAPSE; BORTEZOMIB; TOPOTECAN; MODELS;
D O I
10.1038/bmt.2016.122
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:1279 / 1282
页数:4
相关论文
共 15 条
[1]   Prognostic Value of Minimal Residual Disease Quantification Before Allogeneic Stem-Cell Transplantation in Relapsed Childhood Acute Lymphoblastic Leukemia: The ALL-REZ BFM Study Group [J].
Bader, Peter ;
Kreyenberg, Hermann ;
Henze, Guenter H. R. ;
Eckert, Cornelia ;
Reising, Miriam ;
Willasch, Andre ;
Barth, Andrea ;
Borkhardt, Arndt ;
Peters, Christina ;
Handgretinger, Rupert ;
Sykora, Karl-Walter ;
Holter, Wolfgang ;
Kabisch, Hartmut ;
Klingebiel, Thomas ;
von Stackelberg, Arend .
JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (03) :377-384
[2]   The Anti-CD19 Antibody-Drug Conjugate SAR3419 Prevents Hematolymphoid Relapse Postinduction Therapy in Preclinical Models of Pediatric Acute Lymphoblastic Leukemia [J].
Carol, Hernan ;
Szymanska, Barbara ;
Evans, Kathryn ;
Boehm, Ingrid ;
Houghton, Peter J. ;
Smith, Malcolm A. ;
Lock, Richard B. .
CLINICAL CANCER RESEARCH, 2013, 19 (07) :1795-1805
[3]   Initial Testing of Topotecan by the Pediatric Preclinical Testing Program [J].
Carol, Hernan ;
Houghton, Peter J. ;
Morton, Christopher L. ;
Kolb, E. Anders ;
Gorlick, Richard ;
Reynolds, C. Patrick ;
Kang, Min H. ;
Maris, John M. ;
Keir, Stephen T. ;
Watkins, Amy ;
Smith, Malcolm A. ;
Lock, Richard B. .
PEDIATRIC BLOOD & CANCER, 2010, 54 (05) :707-715
[4]   Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia [J].
Case, Marian ;
Matheson, Elizabeth ;
Minto, Lynne ;
Hassan, Rosline ;
Harrison, Christine J. ;
Bown, Nick ;
Bailey, Simon ;
Vormoor, Josef ;
Hall, Andrew G. ;
Irving, Julie A. E. .
CANCER RESEARCH, 2008, 68 (16) :6803-6809
[5]   Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse [J].
Clappier, Emmanuelle ;
Gerby, Bastien ;
Sigaux, Francois ;
Delord, Marc ;
Touzri, Farah ;
Hernandez, Lucie ;
Ballerini, Paola ;
Baruchel, Andre ;
Pflumio, Francoise ;
Soulier, Jean .
JOURNAL OF EXPERIMENTAL MEDICINE, 2011, 208 (04) :653-661
[6]   Second transplant for acute and chronic leukemia relapsing after first HLA-identical sibling transplant [J].
Eapen, M ;
Giralt, SA ;
Horowitz, MM ;
Klein, JP ;
Wagner, JE ;
Zhang, MJ ;
Tallman, MS ;
Marks, DI ;
Camitta, BM ;
Champlin, RE ;
Ringdén, O ;
Bredeson, CN ;
Martino, R ;
Gale, RP ;
Cairo, MS ;
Litzow, MR ;
deLima, M .
BONE MARROW TRANSPLANTATION, 2004, 34 (08) :721-727
[7]   Phase II study of topotecan in combination with dexamethasone, asparaginase, and vincristine in pediatric patients with acute lymphoblastic leukemia in first relapse [J].
Hijiya, Nobuko ;
Stewart, Clinton F. ;
Zhou, Yinmei ;
Campana, Dario ;
Coustan-Smith, Elaine ;
Rivera, Gaston K. ;
Relling, Mary V. ;
Pui, Ching-Hon ;
Gajjar, Arnar .
CANCER, 2008, 112 (09) :1983-1991
[8]   Initial testing (stage 1) of the proteasome inhibitor bortezomib by the pediatric preclinical testing program [J].
Houghton, Peter J. ;
Morton, Christopher L. ;
Kolb, E. Anders ;
Lock, Richard ;
Carol, Hernan ;
Reynolds, C. Patrick ;
Keshelava, Nino ;
Maris, John M. ;
Keir, Stephen T. ;
Wu, Jianrong ;
Smith, Malcolm A. .
PEDIATRIC BLOOD & CANCER, 2008, 50 (01) :37-45
[9]   Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies [J].
Liem, NLM ;
Papa, RA ;
Milross, CG ;
Schmid, MA ;
Tajbakhsh, M ;
Choi, S ;
Ramirez, CD ;
Rice, AM ;
Haber, M ;
Norris, MD ;
MacKenzie, KL ;
Lock, RB .
BLOOD, 2004, 103 (10) :3905-3914
[10]   Bortezomib with chemotherapy is highly active in advanced B-precursor acute lymphoblastic leukemia: Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) Study [J].
Messinger, Yoav H. ;
Gaynon, Paul S. ;
Sposto, Richard ;
van der Giessen, Jeannette ;
Eckroth, Elena ;
Malvar, Jemily ;
Bostrom, Bruce C. .
BLOOD, 2012, 120 (02) :285-290