AnalyzeNNLS: Magnetic resonance multiexponential decay image analysis

被引：29
作者：
Bjarnason, Thorarin A. [1 ]
Mitchell, J. Ross [1 ,2 ]
机构：
[1] Vancouver Coastal Hlth, Vancouver, BC, Canada
[2] Univ Calgary, Calgary, AB, Canada
来源：
JOURNAL OF MAGNETIC RESONANCE | 2010年 / 206卷 / 02期
关键词：
Magnetic resonance; Quantitative T(2); Matlab; Multiexponential analysis; Visualization; SPIN-SPIN RELAXATION; IN-VIVO; WHITE-MATTER; HUMAN-BRAIN; T-2; RELAXATION; WATER; TISSUE; NMR; DISTRIBUTIONS; MODEL;
D O I：
10.1016/j.jmr.2010.07.008
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Exponential decays are fundamental to magnetic resonance imaging, yet adequately sampling and analyzing multiexponential decays is rarely attempted. The advantage of multiexponential analysis is the quantification of sub-voxel structure caused by water compartmentalization, with application as a non-invasive imaging biomarker for myelin. We have developed AnalyzeNNLS, software designed specifically for multiexponential decay image analysis that has a user-friendly graphical user interface and can analyze data from many MR manufacturers. AnalyzeNNLS is a simple, platform independent analysis tool that was created using the extensive mathematical and visualization libraries in Matlab, and released as open source code allowing scientists to evaluate, scrutinize, improve, and expand. (C) 2010 Elsevier Inc. All rights reserved.
引用
收藏
页码：200 / 204
页数：5
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