Recent human-specific spreading of a subtelomeric domain

被引：33
|
作者：
Monfouilloux, S
Avet-Loiseau, H
Amarger, V
Balazs, I
Pourcel, C
Vergnaud, G
机构：
[1] Hop Nantes, Inst Biol, Lab Rech Genet Especes, F-44035 Nantes, France
[2] Hop Nantes, Inst Biol, UF Cytogenet Hematol, F-44035 Nantes, France
[3] Lifecodes Corp, Stamford, CT 06902 USA
[4] Inst Pasteur, Unite Immunohematol, F-75724 Paris, France
[5] Ctr Etud Bouchet, Genet Mol Lab, F-91710 Vert Le Petit, France
来源：
GENOMICS | 1998年 / 51卷 / 02期
关键词：
D O I：
10.1006/geno.1998.5358
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The recent spreading of a subtelomeric region at nine different human chromosome ends was characterized by a combination of segregation analyses, physical mapping, junction cloning, and FISH investigations. The events occurred very recently in human genome evolution as demonstrated by sequence analysis of different alleles and the single location of the ancestral site at chromosome 17qter in chimpanzee and orangutan. The domain successfully colonized most Ip, 5q, and 6q chromosome ends and is also present at a significant frequency of Gp, 7p, 8p, lip, 15q, and 19p ends. On 6qter, the transposed domain is immediately distal to the highly conserved, single-copy gene PDCD2. (C) 1998 Academic Press.
引用
收藏
页码：165 / 176
页数：12
相关论文
共 50 条
  • [1] Human-specific loss of regulatory DNA and the evolution of human-specific traits
    McLean, Cory Y.
    Reno, Philip L.
    Pollen, Alex A.
    Bassan, Abraham I.
    Capellini, Terence D.
    Guenther, Catherine
    Indjeian, Vahan B.
    Lim, Xinhong
    Menke, Douglas B.
    Schaar, Bruce T.
    Wenger, Aaron M.
    Bejerano, Gill
    Kingsley, David M.
    NATURE, 2011, 471 (7337) : 216 - 219
  • [2] Human-specific loss of regulatory DNA and the evolution of human-specific traits
    Cory Y. McLean
    Philip L. Reno
    Alex A. Pollen
    Abraham I. Bassan
    Terence D. Capellini
    Catherine Guenther
    Vahan B. Indjeian
    Xinhong Lim
    Douglas B. Menke
    Bruce T. Schaar
    Aaron M. Wenger
    Gill Bejerano
    David M. Kingsley
    Nature, 2011, 471 : 216 - 219
  • [3] Re: Human-Specific Loss of Regulatory DNA and the Evolution of Human-Specific Traits
    van Driel, Mels F.
    EUROPEAN UROLOGY, 2011, 60 (05) : 1123 - 1124
  • [4] Human-specific CpG "beacons" identify loci associated with human-specific traits and disease
    Bell, Christopher G.
    Wilson, Gareth A.
    Butcher, Lee M.
    Roos, Christian
    Walter, Lutz
    Beck, Stephan
    EPIGENETICS, 2012, 7 (10) : 1188 - 1199
  • [5] A human-specific gene in microglia
    Hayakawa, T
    Angata, T
    Lewis, AL
    Mikkelsen, TS
    Varki, NM
    Varki, A
    SCIENCE, 2005, 309 (5741) : 1693 - 1693
  • [6] Human-specific duplication and mosaic transcripts: The recent paralogous structure of chromosome 22
    Bailey, JA
    Yavor, AM
    Viggiano, L
    Misceo, D
    Horvath, JE
    Archidiacono, N
    Schwartz, S
    Rocchi, M
    Eichler, EE
    AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 70 (01) : 83 - 100
  • [7] Recent insertion of an Alu element within a polymorphic human-specific Alu insertion
    Comas, D
    Plaza, S
    Calafell, F
    Sajantila, A
    Bertranpetit, J
    MOLECULAR BIOLOGY AND EVOLUTION, 2001, 18 (01) : 85 - 88
  • [8] Human-specific endogenous retroviruses
    Buzdin, Anton
    THESCIENTIFICWORLDJOURNAL, 2007, 7 : 1848 - 1868
  • [9] Potential role of human-specific genes, human-specific microRNAs and human-specific non-coding regulatory RNAs in the pathogenesis of Systemic Sclerosis and Sjogren's Syndrome
    Jimenez, Sergio A.
    Piera-Velazquez, Sonsoles
    AUTOIMMUNITY REVIEWS, 2013, 12 (11) : 1046 - 1051
  • [10] The human-specific action of intermedilysin, a homolog of streptolysin O, is dictated by domain 4 of the protein
    Nagamune, H
    Ohkura, K
    Sukeno, A
    Cowan, G
    Mitchell, TJ
    Ito, W
    Ohnishi, O
    Hattori, K
    Yamato, M
    Hirota, K
    Miyake, Y
    Maeda, T
    Kourai, H
    MICROBIOLOGY AND IMMUNOLOGY, 2004, 48 (09) : 677 - 692
12345