Heart Transplantation in Women

被引：13

作者：

Hasan, Ayesha ^{[1
]}

Kittleson, Michelle M. ^{[2
]}

机构：

[1] Ohio State Univ, Wexner Med Ctr, Heart Failure Fellowship Program, Clin Internal Med,Cardiac Transplant Program, 200 DHLRI,473 West 12th Ave, Columbus, OH 43220 USA

[2] Cedars Sinai Med Ctr, Smidt Heart Inst, Heart Failure Res, Educ Heart Failure & Transplantat, 8536 Wilshire Blvd,Suite 301, Los Angeles, CA 90211 USA

来源：

HEART FAILURE CLINICS | 2019年 / 15卷 / 01期

关键词：

Sensitization; Rejection; Survival; Quality of life; ANTIBODY-MEDIATED REJECTION; ASSOCIATION TASK-FORCE; INTERNATIONAL SOCIETY; CONSENSUS CONFERENCE; PRACTICE GUIDELINES; COMPLEMENT-BINDING; PREGNANCY; RECIPIENTS; OUTCOMES; DISEASE;

D O I：

10.1016/j.hfc.2018.08.012

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Over the past 5 decades, heart transplantation has become an established therapy with greater quality of life and survival than expected from end-stage heart failure. Nonetheless, challenges still exist, especially for women undergoing heart transplantation. Women have greater post-transplant survival than their male counterparts but worse quality of life. Pregnancy may occur, especially because more women are reaching child-bearing age after transplantation. Successful outcomes have been reported but require a systematic multidisciplinary approach. Women are more likely to be sensitized, with preformed anti-human leukocyte antigens antibodies related to prior pregnancies, posing challenges for their pretransplant and post-transplant management.

引用

页码：127 / +

页数：11

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