A new synthetic entry to the indolo[2,3-a]quinolizidine system. Electrophilic cyclizations on the indole ring from 2-(2-piperidyl)indoles

被引：18
作者：
Amat, M
Hadida, S
Sathyanarayana, S
Bosch, J
机构：
[1] Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 17期
关键词：
D O I：
10.1016/0040-4039(96)00472-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new synthetic route to the indolo[2,3-a]quinolizidine system, involving the Pd(0)-catalyzed cross-coupling of a 2-indolylzinc derivative with a 2-halopyridine, stereoselective hydrogenation of the pyridine ring, and electrophilic cyclization upon the indole 3-position from the resulting 2-(2-piperidyl)indole, is reported. (C) 1996 Elsevier Science Ltd.
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页码：3071 / 3074
页数：4
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