Green, One-Pot, Solvent-Free Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles Using a BrOnsted Acidic Ionic Liquid as Novel and Reusable Catalyst

被引：95

作者：

Davoodnia, Abolghasem ^{[1
]}

Heravi, Majid M. ^{[2
]}

Safavi-Rad, Zahra ^{[1
]}

Tavakoli-Hoseini, Niloofar ^{[1
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Fac Sci, Mashhad Branch, Mashhad 91735, Iran

[2] Alzahra Univ, Sch Sci, Dept Chem, Tehran, Iran

来源：

SYNTHETIC COMMUNICATIONS | 2010年 / 40卷 / 17期

关键词：

Bronsted acidic ionic liquids; multicomponent reactions; one-pot synthesis; solvent-free conditions; tetrasubstituted imidazole; TETRASUBSTITUTED IMIDAZOLES; HIGHLY EFFICIENT; ANALOGS;

D O I：

10.1080/00397910903289271

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Methyl-1-(4-sulfonic acid)butylimidazolium hydrogen sulfate [(CH2)4SO3HMIM][HSO4], a BrOnsted acidic ionic liquid, has been used as an efficient, green, and reusable catalyst for the synthesis of 1,2,4,5-tetrasubstituted imidazoles using benzil, an aromatic aldehyde, and a primary amine in the presence of ammonium acetate under solvent-free conditions. The catalyst could be recycled and reused several times without noticeably decreasing the catalytic activity.

引用

页码：2588 / 2597

页数：10

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