ODORANT-BINDING PROTEINS IN INSECTS

被引：330
作者：
Zhou, Jing-Jiang [1 ]
机构：
[1] Insect Mol Biol Grp, Ctr Sustainable Pest & Dis Management, Biol Chem Div, Harpenden, Herts, England
来源：
VITAMINS AND HORMONES: PHEROMONES | 2010年 / 83卷
关键词：
PHEROMONE-SENSITIVE NEURONS; MOSQUITO ANOPHELES-GAMBIAE; MALARIA VECTOR MOSQUITO; ANTHERAEA-POLYPHEMUS; BOMBYX-MORI; GENE FAMILY; SEX-PHEROMONE; GYPSY-MOTH; LIGAND-BINDING; OLFACTORY SENSILLA;
D O I：
10.1016/S0083-6729(10)83010-9
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Our understanding of the molecular and biochemical mechanisms that mediate chemoreception in insects has been greatly improved after the discovery of olfactory and taste receptor proteins. However, after 50 years of the discovery of first insect sex pheromone from the silkmoth Bombyx mori, it is still unclear how hydrophobic compounds reach the dendrites of sensory neurons in vivo across aqueous space and interact with the sensory receptors. The presence of soluble polypeptides in high concentration in the lymph of chemosensilla still poses unanswered questions. More than two decades after their discovery and despite the wealth of structural and biochemical information available, the physiological function of odorant-binding proteins (OBPs) is not well understood. Here, I review the structural properties of different subclasses of insect OBPs and their binding to pheromones and other small ligands. Finally, I discuss current ideas and models on the role of such proteins in insect chemoreception. (C) 2010 Elsevier Inc.
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页码：241 / 272
页数：32
相关论文
共 127 条
[1]   Purification, structural characterization, cloning and immunocytochemical localization of chemoreception proteins from Schistocerca gregaria [J].
Angeli, S ;
Ceron, F ;
Scaloni, A ;
Monti, M ;
Monteforti, G ;
Minnocci, A ;
Petacchi, R ;
Pelosi, P .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1999, 262 (03) :745-754
[2]   ADAPTATION OF ANTENNAL NEURONS IN MOTHS IS ASSOCIATED WITH CESSATION OF PHEROMONE-MEDIATED UPWIND FLIGHT [J].
BAKER, TC ;
HANSSON, BS ;
LOFSTEDT, C ;
LOFQVIST, J .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (24) :9826-9830
[3]   Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo [J].
Benton, R ;
Sachse, S ;
Michnick, SW ;
Vosshall, LB .
PLOS BIOLOGY, 2006, 4 (02) :240-257
[4]   An essential role for a CD36-related receptor in pheromone detection in Drosophila [J].
Benton, Richard ;
Vannice, Kirsten S. ;
Vosshall, Leslie B. .
NATURE, 2007, 450 (7167) :289-U13
[5]   Probing a pheromone binding protein of the silkmoth Antheraea polyphemus by endogenous tryptophan fluorescence [J].
Bette, S ;
Breer, H ;
Krieger, J .
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2002, 32 (03) :241-246
[6]   POTENT SEX ATTRACTANT OF GYPSY MOTH - ITS ISOLATION, IDENTIFICATION, AND SYNTHESIS [J].
BIERL, BA ;
BEROZA, M ;
COLLIER, CW .
SCIENCE, 1970, 170 (3953) :87-+
[7]   Isolation of cDNA clones encoding putative odourant binding proteins from the antennae of the malaria-transmitting mosquito, Anopheles gambiae [J].
Biessmann, H ;
Walter, MF ;
Dimitratos, S ;
Woods, D .
INSECT MOLECULAR BIOLOGY, 2002, 11 (02) :123-132
[8]   THRESHOLD AND ODOR SPECIFICITY OF PHEROMONE-SENSITIVE NEURONS IN THE DEUTOCEREBRUM OF ANTHERAEA-PERNYI AND ANTHERAEA-POLYPHEMUS (SATURNIDAE) [J].
BOECKH, J ;
BOECKH, V .
JOURNAL OF COMPARATIVE PHYSIOLOGY, 1979, 132 (03) :235-242
[9]   Molecular characterization of the Aedes aegypti odorant receptor gene family [J].
Bohbot, J. ;
Pitts, R. J. ;
Kwon, H.-W. ;
Ruetzler, M. ;
Robertson, H. M. ;
Zwiebel, L. J. .
INSECT MOLECULAR BIOLOGY, 2007, 16 (05) :525-537
[10]   RAPID KINETICS OF 2ND MESSENGER FORMATION IN OLFACTORY TRANSDUCTION [J].
BREER, H ;
BOEKHOFF, I ;
TAREILUS, E .
NATURE, 1990, 345 (6270) :65-68
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