Covalent Organic Frameworks with Nanopores for Biological Applications: A Review

被引：30
作者：
Mal, Arindam [1 ]
Ding, Huimin [1 ]
Li, Mengsi [1 ]
Li, Weixu [1 ]
Wang, Cheng [1 ]
机构：
[1] Wuhan Univ, Coll Chem & Mol Sci, Sauvage Ctr Mol Sci, Wuhan 430072, Peoples R China
来源：
ACS APPLIED NANO MATERIALS | 2022年 / 5卷 / 10期
基金：
中国国家自然科学基金; 中国博士后科学基金;
关键词：
covalent organic frameworks; drug delivery; bioimaging; phototherapy; antibacterial; NANOSHEETS; CRYSTALLINE; DESIGN;
D O I：
10.1021/acsanm.2c01517
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Covalent organic frameworks (COFs), a class of functional nanoporous materials, not only hold the fundamental characteristics of reticular chemistry but also have advantages of robust covalent connectivity and chromophoric networks with extended pi-conjugation. Therefore, the integration of biologically relevant building blocks to form biocompatible COFs through tailor-made design principles will make them highly suitable for biomedical research. Herein, we briefly describe the most important biological applications of nanoscale COFs, such as drug delivery, bioimaging, phototherapy, and antibacterial proper-ties. Finally, the existing challenges and prospects of COF-based nanomaterials for advanced biomedical applications have been discussed.
引用
收藏
页码：13972 / 13984
页数：13
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