CCR 20th Anniversary Commentary: Stayin' Alive-Antiapoptotic Proteins and Breast Cancer

被引:0
作者
Yee, Douglas [1 ]
机构
[1] Univ Minnesota, Mason Canc Ctr, Dept Med, Minneapolis, MN 55455 USA
关键词
SURVIVIN ANTISENSE OLIGONUCLEOTIDE; CELL LUNG-CANCER; TARGETING SURVIVIN; PHASE; SUPPRESSOR; APOPTOSIS; LY2181308; YM155;
D O I
10.1158/1078-0432.CCR-14-2548
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The control of cell death involves a complex interaction of multiple proteins. In a study published in the January 1, 2000, issue of Clinical Cancer Research, Tanaka and colleagues demonstrated that one of the proapoptotic proteins, survivin, was frequently expressed in breast cancer. In the subsequent years, effectors of apoptosis have translated into important prognostic indicators and potential therapeutic targets. - © 2015 American Association for Cancer Research.
引用
收藏
页码:665 / 666
页数:2
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