Fiber-reinforced scaffolds in soft tissue engineering

被引:91
作者
Pei, Baoqing [1 ]
Wang, Wei [1 ]
Fan, Yubo [1 ]
Wang, Xiumei [2 ]
Watari, Fumio [3 ]
Li, Xiaoming [1 ]
机构
[1] Beihang Univ, Sch Biol Sci & Med Engn, Minist Educ, Key Lab Biomechan & Mech, Beijing 100191, Peoples R China
[2] Tsinghua Univ, State Key Lab New Ceram & Fine Proc, Beijing 100084, Peoples R China
[3] Hokkaido Univ, Grad Sch Dent Med, Dept Biomed Mat & Engn, Sapporo, Hokkaido 0608586, Japan
基金
中国国家自然科学基金;
关键词
scaffolds; reinforce; fibers; soft tissue; BIODEGRADABLE POLYURETHANE SCAFFOLDS; MECHANICAL-PROPERTIES; ELASTOMERIC SCAFFOLDS; NANOFIBROUS SCAFFOLD; MATRIX ELASTICITY; VASCULAR GRAFTS; SILK SCAFFOLDS; COLLAGEN; ELECTROSPUN; HYDROGEL;
D O I
10.1093/rb/rbx021
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Soft tissue engineering has been developed as a new strategy for repairing damaged or diseased soft tissues and organs to overcome the limitations of current therapies. Since most of soft tissues in the human body are usually supported by collagen fibers to form a three-dimensional microstructure, fiber-reinforced scaffolds have the advantage to mimic the structure, mechanical and biological environment of natural soft tissues, which benefits for their regeneration and remodeling. This article reviews and discusses the latest research advances on design and manufacture of novel fiber-reinforced scaffolds for soft tissue repair and how fiber addition affects their structural characteristics, mechanical strength and biological activities in vitro and in vivo. In general, the concept of fiber-reinforced scaffolds with adjustable microstructures, mechanical properties and degradation rates can provide an effective platform and promising method for developing satisfactory biomechanically functional implantations for soft tissue engineering or regenerative medicine.
引用
收藏
页码:257 / 268
页数:12
相关论文
共 91 条
[31]   Fabrication of fibrinogen/P(LLA-CL) hybrid nanofibrous scaffold for potential soft tissue engineering applications [J].
He, Chuanglong ;
Xu, Xiaohong ;
Zhang, Fan ;
Cao, Lijun ;
Feng, Wei ;
Wang, Hongsheng ;
Mo, Xiumei .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2011, 97A (03) :339-347
[32]   Three-dimensional electrospun ECM-based hybrid scaffolds for cardiovascular tissue engineering [J].
Heydarkhan-Hagvall, Sepideh ;
Schenke-Layland, Katja ;
Dhanasopon, Andrew P. ;
Rofail, Fady ;
Smith, Hunter ;
Wu, Benjamin M. ;
Shemin, Richard ;
Beygui, Ramin E. ;
MacLellan, William R. .
BIOMATERIALS, 2008, 29 (19) :2907-2914
[33]  
Hodde J, 2006, ANZ J SURG, V76, P1096, DOI 10.1111/j.1445-2197.2006.03948.x
[34]   Chronic rupture of tendo Achillis - Long-term results of operative management using polyester tape [J].
Jennings, AG ;
Sefton, GK .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2002, 84B (03) :361-363
[35]   Perspectives in Multiphasic Osteochondral Tissue Engineering [J].
Jeon, June E. ;
Vaquette, Cedryck ;
Klein, Travis J. ;
Hutmacher, Dietmar W. .
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, 2014, 297 (01) :26-35
[36]  
Kumar VA, 2013, BIOMATER SCI-UK, V1, P1193, DOI [10.1039/c3bm60129c, 10.1039/C3BM60129C]
[37]   TISSUE ENGINEERING [J].
LANGER, R ;
VACANTI, JP .
SCIENCE, 1993, 260 (5110) :920-926
[38]   Ligament tissue engineering: An evolutionary materials science approach [J].
Laurencin, CT ;
Freeman, JW .
BIOMATERIALS, 2005, 26 (36) :7530-7536
[39]   Tissue Engineering of the Intervertebral Disc With Cultured Nucleus Pulposus Cells Using Atelocollagen Scaffold and Growth Factors [J].
Lee, Kwang-Il ;
Moon, Seong-Hwan ;
Kim, Hyang ;
Kwon, Un-Hye ;
Kim, Ho-Joong ;
Park, Si-Nae ;
Suh, Hwal ;
Lee, Hwan-Mo ;
Kim, Hak-Sun ;
Chun, Heoung-Jae ;
Kwon, Il-Keun ;
Jang, Ju-Woong .
SPINE, 2012, 37 (06) :452-458
[40]   Construction of collagen II/hyaluronate/chondroitin-6-sulfate tri-copolymer scaffold for nucleus pulposus tissue engineering and preliminary analysis of its physico-chemical properties and biocompatibility [J].
Li, Chang-qing ;
Huang, Bo ;
Luo, Gang ;
Zhang, Chuan-zhi ;
Zhuang, Ying ;
Zhou, Yue .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2010, 21 (02) :741-751