Fiber-reinforced scaffolds in soft tissue engineering

被引：91

作者：

Pei, Baoqing ^{[1
]}

Wang, Wei ^{[1
]}

Fan, Yubo ^{[1
]}

Wang, Xiumei ^{[2
]}

Watari, Fumio ^{[3
]}

Li, Xiaoming ^{[1
]}

机构：

[1] Beihang Univ, Sch Biol Sci & Med Engn, Minist Educ, Key Lab Biomechan & Mech, Beijing 100191, Peoples R China

[2] Tsinghua Univ, State Key Lab New Ceram & Fine Proc, Beijing 100084, Peoples R China

[3] Hokkaido Univ, Grad Sch Dent Med, Dept Biomed Mat & Engn, Sapporo, Hokkaido 0608586, Japan

来源：

REGENERATIVE BIOMATERIALS | 2017年 / 4卷 / 04期

基金：

中国国家自然科学基金;

关键词：

scaffolds; reinforce; fibers; soft tissue; BIODEGRADABLE POLYURETHANE SCAFFOLDS; MECHANICAL-PROPERTIES; ELASTOMERIC SCAFFOLDS; NANOFIBROUS SCAFFOLD; MATRIX ELASTICITY; VASCULAR GRAFTS; SILK SCAFFOLDS; COLLAGEN; ELECTROSPUN; HYDROGEL;

D O I：

10.1093/rb/rbx021

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Soft tissue engineering has been developed as a new strategy for repairing damaged or diseased soft tissues and organs to overcome the limitations of current therapies. Since most of soft tissues in the human body are usually supported by collagen fibers to form a three-dimensional microstructure, fiber-reinforced scaffolds have the advantage to mimic the structure, mechanical and biological environment of natural soft tissues, which benefits for their regeneration and remodeling. This article reviews and discusses the latest research advances on design and manufacture of novel fiber-reinforced scaffolds for soft tissue repair and how fiber addition affects their structural characteristics, mechanical strength and biological activities in vitro and in vivo. In general, the concept of fiber-reinforced scaffolds with adjustable microstructures, mechanical properties and degradation rates can provide an effective platform and promising method for developing satisfactory biomechanically functional implantations for soft tissue engineering or regenerative medicine.

引用

页码：257 / 268

页数：12

共 91 条

[1] Strong fiber-reinforced hydrogel [J].

Agrawal, Animesh ;

Rahbar, Nima ;

Calvert, Paul D. .

ACTA BIOMATERIALIA, 2013, 9 (02) :5313-5318

[2] Improving the mechanical properties of chitosan-based heart valve scaffolds using chitosan fibers [J].

Albanna, Mohammad Z. ;

Bou-Akl, Therese H. ;

Walters, Henry L., III ;

Matthew, Howard W. T. .

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 2012, 5 (01) :171-180

[3] Nerve regeneration and elastin formation within poly(glycerol sebacate)-based synthetic arterial grafts one-year post-implantation in a rat model [J].

Allen, Robert A. ;

Wu, Wei ;

Yao, Mingyi ;

Dutta, Debaditya ;

Duan, Xinjie ;

Bachman, Timothy N. ;

Champion, Hunter C. ;

Stolz, Donna B. ;

Robertson, Anne M. ;

Kim, Kang ;

Isenberg, Jeffrey S. ;

Wang, Yadong .

BIOMATERIALS, 2014, 35 (01) :165-173

[4] Effects of collagen membranes enriched with in vitro-differentiated N1E-115 cells on rat sciatic nerve regeneration after end-to-end repair [J].

Amado, Sandra ;

Rodrigues, Jorge M. ;

Luis, Ana L. ;

Armada-da-Silva, Paulo A. S. ;

Vieira, Marcia ;

Gartner, Andrea ;

Simoes, Maria J. ;

Veloso, Antonio P. ;

Fornaro, Michele ;

Raimondo, Stefania ;

Varejao, Artur S. P. ;

Geuna, Stefano ;

Mauricio, Ana C. .

JOURNAL OF NEUROENGINEERING AND REHABILITATION, 2010, 7

[5] Composite hydrogels for intervertebral disc prostheses [J].

Ambrosio, L ;

Netti, PA ;

Iannace, S ;

Huang, SJ ;

Nicolais, L .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 1996, 7 (05) :251-254

[6]

[Anonymous], ACT PLAN PR IN PRESS

[7] The relationship between the mechanical properties and cell behaviour on PLGA and PCL scaffolds for bladder tissue engineering [J].

Baker, Simon C. ;

Rohman, Geraldine ;

Southgate, Jennifer ;

Cameron, Neil R. .

BIOMATERIALS, 2009, 30 (07) :1321-1328

[8] Cell-delivery therapeutics for adipose tissue regeneration [J].

Bauer-Kreisel, Petra ;

Goepferich, Achim ;

Blunk, Torsten .

ADVANCED DRUG DELIVERY REVIEWS, 2010, 62 (7-8) :798-813

[9] A brief review of the modelling of the time dependent mechanical properties of tissue engineering scaffolds [J].

Bawolin N.K. ;

Zhang W.J. ;

Chen X.B. .

Journal of Biomimetics, Biomaterials, and Tissue Engineering, 2010, 6 (01) :19-33

[10] Application of polymeric nanofibers in soft tissues regeneration [J].

Biazar, Esmaeil .

POLYMERS FOR ADVANCED TECHNOLOGIES, 2016, 27 (11) :1404-1412

← 1 2 3 4 5 6 7 8 9 10 →