Clinical-epidemiological and radiological characteristics of stroke patients: A multicentre study

被引:2
作者
Kunt, Refik [1 ]
Cinar, Bilge Piri [2 ]
Yuksel, Burcu [3 ]
Gulluoglu, Halil [4 ]
Sayilir, Idris [5 ]
Uslu, Sibel Celiker [5 ]
Goksu, Eylem Ozaydin [3 ]
Bulbul, Nazli Gamze [6 ]
Yildiz, Baykal [7 ]
Oz, Didem [8 ]
Keskin, Ahmet Onur [9 ]
Korucu, Osman [10 ]
Akpinar, Cetin Kursad [11 ]
Solmaz, Volkan [12 ]
Akpinar, Meliha [12 ]
Altunc, Fatma Zehra [3 ]
Elmas, Zeynep [4 ]
Buyukuysal, Cagatay [13 ]
Ekici, Mustafa [14 ]
Guvendi, Guven [15 ]
机构
[1] Izmir Demokrasi Univ, Sch Med, Dept Neurol, Izmir, Turkey
[2] Zonguldak Bulent Ecevit Univ, Sch Med, Dept Neurol, Zonguldak, Turkey
[3] Antalya Training & Res Hosp, Neurol Clin, Antalya, Turkey
[4] Medicalpk Izmir Hosp, Neurol Clin, Izmir, Turkey
[5] Samsun Training & Res Hosp, Neurol Clin, Samsun, Turkey
[6] Mus State Hosp, Clin Neurol, Mus, Turkey
[7] Dr Ersin Arslan Training & Res Hosp, Neurol Clin, Gaziantep, Turkey
[8] Dokuz Eylul Univ, Neurol Clin, Izmir, Turkey
[9] Eskisehir Yunus Emre State Hosp, Neurol Clin, Eskisehir, Turkey
[10] Kecioren Training & Res Hosp, Neurol Clin, Ankara, Turkey
[11] Ankara Numune Training & Res Hosp, Neurol Clin, Ankara, Turkey
[12] Trakya Univ, Fac Med, Dept Neurol, Edirne, Turkey
[13] Bulent Ecevit Univ, Fac Med, Dept Stat, Zonguldak, Turkey
[14] Ataturk State Hosp, Emergency Med Clin, Aydin, Turkey
[15] Izmir Demokrasi Univ, Sch Med, Dept Physiol, Izmir, Turkey
关键词
RISK-FACTORS; INTRACEREBRAL HEMORRHAGE; GLOBAL BURDEN; ATRIAL-FIBRILLATION; THYROID-FUNCTION; ISCHEMIC-STROKE; WARFARIN; COUNTRIES; HYPERCHOLESTEROLEMIA; METAANALYSIS;
D O I
10.1111/ijcp.14963
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction and Aim Stroke is the leading cause of disability in adults and the second most common cause of death, at a rate of 11.8% worldwide. The purpose of this study was to examine the aetiological, demographic, and clinical characteristics of patients admitted to hospital because of acute strokes. Materials and Methods This multicentre study retrieved information for all patients admitted to hospital because of an acute cerebrovascular event over a six-month period, and sociodemographic, aetiological, and clinical characteristics were recorded. Results A total of 1136 patients, 520 of whom were women (45.7%), with a mean age of 70.3 +/- 12.8 years, were included in the study. Of these, 967 were diagnosed with ischaemic stroke (IS) (85.1%), 99 with haemorrhagic stroke (HS) (8.7%), and 70 with transient ischaemic attack (6.1%). The most common risk factor for stroke was hypertension (73%). Carotid disease and hyperlipidaemia rates were higher in patients with HS. Numbers of functionally dependent patients with severe neurological status according to the National Institutes of Health Stroke Scale and modified Rankin scale were significantly higher in the HS group (P < .001). When IS was classified according to the Trial of Org 10172 in Acute Stroke Treatment, small vessel disease emerged as the most common cause (41%). The most common lesion localisations were the parietal lobe (23%) in the IS group and the thalamus (35.3%) in the HS group. Eighty-eight patients (7.7%), 62 (6.4%) in the ischaemic subgroup, and 26 (26.3%) in the haemorrhagic subgroup, died within the first month. Conclusion Current and accurate evaluations of stroke aetiology are essential for stroke prevention and treatment planning. This study, shows that no change occurred in the aetiology of stroke and epidemiological characteristics and that accurate identification of modifiable stroke risk factors is still a major goal.
引用
收藏
页数:10
相关论文
共 59 条
  • [1] CLASSIFICATION OF SUBTYPE OF ACUTE ISCHEMIC STROKE - DEFINITIONS FOR USE IN A MULTICENTER CLINICAL-TRIAL
    ADAMS, HP
    BENDIXEN, BH
    KAPPELLE, LJ
    BILLER, J
    LOVE, BB
    GORDON, DL
    MARSH, EE
    KASE, CS
    WOLF, PA
    BABIKIAN, VL
    LICATAGEHR, EE
    ALLEN, N
    BRASS, LM
    FAYAD, PB
    PAVALKIS, FJ
    WEINBERGER, JM
    TUHRIM, S
    RUDOLPH, SH
    HOROWITZ, DR
    BITTON, A
    MOHR, JP
    SACCO, RL
    CLAVIJO, M
    ROSENBAUM, DM
    SPARR, SA
    KATZ, P
    KLONOWSKI, E
    CULEBRAS, A
    CAREY, G
    MARTIR, NI
    FICARRA, C
    HOGAN, EL
    CARTER, T
    GURECKI, P
    MUNTZ, BK
    RAMIREZLASSEPAS, M
    TULLOCH, JW
    QUINONES, MR
    MENDEZ, M
    ZHANG, SM
    ALA, T
    JOHNSTON, KC
    ANDERSON, DC
    TARREL, RM
    NANCE, MA
    BUDLIE, SR
    DIERICH, M
    HELGASON, CM
    HIER, DB
    SHAPIRO, RA
    [J]. STROKE, 1993, 24 (01) : 35 - 41
  • [2] Sex Differences in Stroke Epidemiology A Systematic Review
    Appelros, Peter
    Stegmayr, Birgitta
    Terent, Andreas
    [J]. STROKE, 2009, 40 (04) : 1082 - 1090
  • [3] Thyroid Function Within the Normal Range, Subclinical Hypothyroidism, and the Risk of Atrial Fibrillation
    Baumgartner, Christine
    da Costa, Bruno R.
    Collet, Tinh-Hai
    Feller, Martin
    Floriani, Carmen
    Bauer, Douglas C.
    Cappola, Anne R.
    Heckbert, Susan R.
    Ceresini, Graziano
    Gussekloo, Jacobijn
    den Elzen, Wendy P. J.
    Peeters, Robin P.
    Luben, Robert
    Voelzke, Henry
    Doerr, Marcus
    Walsh, John P.
    Bremner, Alexandra
    Iacoviello, Massimo
    Macfarlane, Peter
    Heeringa, Jan
    Stott, David J.
    Westendorp, Rudi G. J.
    Khaw, Kay-Tee
    Magnani, Jared W.
    Aujesky, Drahomir
    Rodondi, Nicolas
    [J]. CIRCULATION, 2017, 136 (22) : 2100 - 2116
  • [4] Benjamin EJ, 2019, CIRCULATION, V139, pE56, DOI [10.1161/CIR.0000000000000746, 10.1161/CIR.0000000000000659]
  • [5] Worldwide reported use of IV tissue plasminogen activator for acute ischemic stroke
    Berkowitz, Aaron L.
    Mittal, Manoj K.
    McLane, Hannah C.
    Shen, Gordon C.
    Muralidharan, RajaNandini
    Lyons, Jennifer L.
    Shinohara, Russell T.
    Shuaib, Ashfaq
    Mateen, Farrah J.
    [J]. INTERNATIONAL JOURNAL OF STROKE, 2014, 9 (03) : 349 - 355
  • [6] Hypercholesterolemia as one of the risk factors of intracerebral hemorrhage
    Bozluolcay, Melda
    Nalbantoglu, Mecbure
    Gozubatik-Celik, R. Gokcen
    Benbir, Gulcin
    Akalin, Mehmet Ali
    Erkol, Gokhan
    [J]. ACTA NEUROLOGICA BELGICA, 2013, 113 (04) : 459 - 462
  • [7] National Institutes of Health Stroke Scale An Alternative Primary Outcome Measure for Trials of Acute Treatment for Ischemic Stroke
    Chalos, Vicky
    van der Ende, Nadinda A. M.
    Lingsma, Hester F.
    Mulder, Maxim J. H. L.
    Venema, Esmee
    Dijkland, Simone A.
    Berkhemer, Olvert A.
    Yoo, Albert J.
    Broderick, Joseph P.
    Palesch, Yuko Y.
    Yeatts, Sharon D.
    Roos, Yvo B. W. E. M.
    van Oostenbrugge, Robert J.
    van Zwam, Wim H.
    Majoie, Charles B. L. M.
    van der Lugt, Aad
    Roozenbeek, Bob
    Dippel, Diederik W. J.
    Fransen, Puck S. S.
    Beumer, Debbie
    van den Berg, Lucie A.
    Schonewille, Wouter J.
    Vos, Jan Albert
    Nederkoorn, Paul J.
    Wermer, Marieke J. H.
    van Walderveen, Marianne A. A.
    Staals, Julie
    Hofmeijer, Jeannette
    van Oostayen, Jacques A.
    Nijeholt, Geert J. Lycklama A.
    Boiten, Jelis
    Brouwer, Patrick A.
    Emmer, Bart J.
    de Bruijn, Sebastiaan F.
    van Dijk, Lukas C.
    Kappelle, L. Jaap
    Lo, Rob H.
    van Dijk, Ewoud J.
    de Vries, Joost
    de Kort, Paul L. M.
    van Rooij, Willem Jan J.
    van den Berg, Jan S. P.
    van Hasselt, Boudewijn A. A. M.
    Aerden, Leo A. M.
    Dallinga, Rene J.
    Visser, Marieke C.
    Bot, Joseph C. J.
    Vroomen, Patrick C.
    Eshghi, Omid
    Schreuder, Tobien H. C. M. L.
    [J]. STROKE, 2020, 51 (01) : 282 - 290
  • [8] Dabigatran versus Warfarin in Patients with Atrial Fibrillation.
    Connolly, Stuart J.
    Ezekowitz, Michael D.
    Yusuf, Salim
    Eikelboom, John
    Oldgren, Jonas
    Parekh, Amit
    Pogue, Janice
    Reilly, Paul A.
    Themeles, Ellison
    Varrone, Jeanne
    Wang, Susan
    Alings, Marco
    Xavier, Denis
    Zhu, Jun
    Diaz, Rafael
    Lewis, Basil S.
    Darius, Harald
    Diener, Hans-Christoph
    Joyner, Campbell D.
    Wallentin, Lars
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (12) : 1139 - 1151
  • [9] Intracerebral hemorrhage location and outcome among INTERACT2 participants
    Delcourt, Candice
    Sato, Shoichiro
    Zhang, Shihong
    Sandset, Else Charlotte
    Zheng, Danni
    Chen, Xiaoying
    Hackett, Maree L.
    Arima, Hisatomi
    Hata, Jun
    Heeley, Emma
    Salman, Rustam Al-Shahi
    Robinson, Thompson
    Davies, Leo
    Lavados, Pablo M.
    Lindley, Richard I.
    Stapf, Christian
    Chalmers, John
    Anderson, Craig S.
    [J]. NEUROLOGY, 2017, 88 (15) : 1408 - 1414
  • [10] Global burden of stroke and risk factors in 188 countries, during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013
    Feigin, Valery L.
    Roth, Gregory A.
    Naghavi, Mohsen
    Parmar, Priya
    Krishnamurthi, Rita
    Chugh, Sumeet
    Mensah, George A.
    Norrving, Bo
    Shiue, Ivy
    Ng, Marie
    Estep, Kara
    Cercy, Kelly
    Murray, Christopher J. L.
    Forouzanfar, Mohammad H.
    [J]. LANCET NEUROLOGY, 2016, 15 (09) : 913 - 924