Synthesis and biological evaluation of novel dibenzofluorene derivatives as anticancer agents

被引:8
作者
Banik, Bimal K. [1 ]
Mukhopadhyay, Chhanda [2 ]
Becker, Frederick F. [2 ]
机构
[1] Univ Texas Pan Amer, Dept Chem, Edinburg, TX 78539 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Mol Pathol, Unit 951, Houston, TX 77504 USA
关键词
dibenzofluorene; synthesis; biological evaluation; anticancer agent; POLYCYCLIC AROMATIC-COMPOUNDS;
D O I
10.3892/ol_00000055
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The novel synthesis of dibenzofluorene has been achieved by a cyclodehydration method Several derivatives have also been prepared using this hydrocarbon These compounds have been tested against a number of cancer cell lines in vitro, and useful selectivity has been observed
引用
收藏
页码:309 / 311
页数:3
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