Activity and attention in zinc-deprived adolescent monkeys

被引:53
作者
Golub, MS
Takeuchi, PT
Keen, CL
Hendrickx, AG
Gershwin, ME
机构
[1] UNIV CALIF DAVIS,DEPT INTERNAL MED,DAVIS,CA 95616
[2] UNIV CALIF DAVIS,DEPT NUTR,DAVIS,CA 95616
[3] UNIV CALIF DAVIS,DEPT ANAT,DAVIS,CA 95616
关键词
monkeys; zinc deprivation; sleep; energy expenditure; attention; vigilance; activity; adolescence; development;
D O I
10.1093/ajcn/64.6.908
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Lethargy is characteristic of malnourished populations, but little is known about the biologic mechanism or consequences for cognitive performance. In the current experiment, 24-h activity patterns and performance of an attention task were studied in adolescent female monkeys (18-33 mo of age, n = 10/group) under conditions of moderate dietary zinc deprivation (2 mu g Zn/g diet) and adequate dietary zinc (50 mu g Zn/g). There were progressive decreases in daytime activity levels in the zinc-deprived group followed by slowing of growth around the time of the growth spurt. Attention performance was also impaired before the onset of growth retardation. Zinc-deprived monkeys failed to show the shift to later initiation of the rest phase of the diurnal cycle seen in controls in late adolescence. These data support previous findings that activity and attention can be affected during early stages of zinc deprivation before the onset of growth retardation.
引用
收藏
页码:908 / 915
页数:8
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