The stereoselective synthesis of a key intermediate of the trinem antibiotic Sanfetrinem

被引:22
作者
Ghiron, C [1 ]
Piga, E [1 ]
Rossi, T [1 ]
Tamburini, B [1 ]
Thomas, RJ [1 ]
机构
[1] GLAXO WELLCOME SPA,MED RES CTR,I-37135 VERONA,ITALY
关键词
D O I
10.1016/0040-4039(96)00682-X
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
By modulating the reactivity of the Lewis acid promoter it was possible to obtain, in a single stereoselective condensation step, the methoxyketone 7, an advanced intermediate in the synthesis of Sanfetrinem GV104326. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码:3891 / 3894
页数:4
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