The MET receptor tyrosine kinase in invasion and metastasis

被引：212

作者：

Benvenuti, Silvia ^{[1
]}

Comoglio, Paolo M. ^{[1
]}

机构：

[1] Univ Turin, IRCCS, Sch Med, Inst Canc Res & Treatment,Div Mol Oncol, I-10060 Candiolo, Torino, Italy

来源：

JOURNAL OF CELLULAR PHYSIOLOGY | 2007年 / 213卷 / 02期

关键词：

D O I：

10.1002/jcp.21183

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Various cytokines and soluble growth factors upon interaction with their membrane receptors are responsible for inducing cellular proliferation, differentiation, movement, and protection from anoikis (a planned suicide activated by normal cells in absence of attachment to neighboring cells or extracellular matrix (EMC)). Among those soluble factors a major position is exerted by hepatocyte growth factor (HGF) together with its receptor MET and macrophage-stimulating protein (MSP) in cooperation with its receptor RON.

引用

收藏

页码：316 / 325

页数：10

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[21] Dysregulation of Met receptor tyrosine kinase activity in invasive tumors [J].

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[22] A NOVEL PUTATIVE RECEPTOR PROTEIN TYROSINE KINASE OF THE MET FAMILY [J].

RONSIN, C ;

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ONCOGENE, 1993, 8 (05) :1195-1202

[23] Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor [J].

Jeffers, M ;

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Fiscella, M ;

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[24] AXL and MET receptor tyrosine kinases are essential for lung cancer metastasis [J].

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[27] The hepatocyte growth factor receptor, Met, in prostate cancer invasion and metastasis [J].

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[29] Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation [J].

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[30] MET tyrosine kinase inhibitors [J].

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