Panhypopituitarism presentation with acute renal failure associated with rhabdomyolysis

A 30-year woman developed rhabdomyolysis and acute renal failure. She had history of amenorrhea after her last delivery. On admission, she was pate, afebrile and ill, had slight tenderness of the muscles. Her muscle enzyme was high and her renal function decreased rapidly, suggesting rhabdomyolysis. Her laboratory investigation was compatible with panhypopituitarism. Treatment was started with levothyroxine and Hydrocortisone. Her renal function recovered completety with conservative treatment without need of dialysis. The present case suggests that rhabdomyolysis could occur in patient with central hypothyroidism.