Alpha-radioimmunotherapy:: a review of recent developments

被引：3

作者：

Supiot, S. ^{[1
,2
]}

Thillays, F. ^{[1
]}

Rio, E. ^{[1
]}

Mahe, M. -A. ^{[1
]}

Barbet, F. -J. ^{[2
]}

Kraeber-Bodere, F. ^{[2
]}

Cherel, M. ^{[2
]}

机构：

[1] Ctr Rene Gauducheau, Serv Radiotherapie, F-44800 Nantes, France

[2] INSERM, U601, Dept Rech Cancerol, F-44093 Nantes 01, France

来源：

CANCER RADIOTHERAPIE | 2007年 / 11卷 / 05期

关键词：

high Linear Energy Transfer particles; radiotherapy; alpha-radioimmunotherapy;

D O I：

10.1016/j.canrad.2007.05.001

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The use of heavy particles in the treatment of cancer is increasing remarkably, whether with external radiation or using a vector such as an antibody in radioimmunotherapy. Recent pre-clinical and clinical developments of alpha-radioimmunotherapy have provided more interesting information in parallel of the use of high Linear Energy Transfer (LET) external irradiation. This review aims at presenting recent advances of this therapeutic approach, and at detailing the biological specificities of this kind of radiation. (C) 2007 Elsevier Masson SAS. Tons droits reserves.

引用

页码：252 / 259

页数：8

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