Low-Grade Glioma Radiotherapy Treatment and Trials

被引：87

作者：

Wang, Tony J. C. ^{[1
,2
]}

Mehta, Minesh P. ^{[3
]}

机构：

[1] Columbia Univ, Med Ctr, Dept Radiat Oncol, 622 West 168th St,BNH B-11, New York, NY 10032 USA

[2] Columbia Univ, Med Ctr, Herbert Irving Comprehens Canc Ctr, 630 West 168th St, New York, NY 10032 USA

[3] Baptist Hosp Miami, Miami Canc Inst, 8900 North Kendall Dr, Miami, FL 33176 USA

来源：

NEUROSURGERY CLINICS OF NORTH AMERICA | 2019年 / 30卷 / 01期

关键词：

Low-grade glioma; Radiotherapy; Trials; INTENSITY-MODULATED RADIOTHERAPY; RADIATION-THERAPY; EORTC; 22033-26033; RANDOMIZED-TRIAL; PROTON THERAPY; OPEN-LABEL; PHASE-II; RISK; IDH; CHEMOTHERAPY;

D O I：

10.1016/j.nec.2018.08.008

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Low-grade gliomas represent an important class of primary brain tumors. They account for approximately 20% of primary brain tumors and typically present in the fourth decade of life. Standard management gliomas involves observation, surgery, chemotherapy, and/or radiotherapy. Treatment decisions are based on many factors including prognostic molecular markers, potential benefits of increased progression-free survival, and potential long-term treatment complications. Recent studies have improved our understanding regarding therapeutic interventions. This review provides an overview of low-grade glioma and discusses the roles of radiation therapy. We discuss advances in techniques and recent and ongoing radiation therapy-related clinical trials for low-grade gliomas.

引用

页码：111 / +

页数：9

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