Cosmic radiation and cancer: is there a link?

被引：20

作者：

Di Trolio, Rossella ^{[1
]}

Di Lorenzo, Giuseppe ^{[2
]}

Fumo, Bruno ^{[3
]}

Ascierto, Paolo A. ^{[1
]}

机构：

[1] Natl Tumor Fdn, G Pascale Inst, Dept Melanoma Sarcoma & Head & Neck Canc, Unit Med Oncol & Innovat Therapy, Naples, Italy

[2] Univ Naples Federico II, Dept Endocrinol & Oncol, Med Oncol, Naples, Italy

[3] Hlth Care Navigators Serv, Minist Hlth, Naples, Italy

来源：

FUTURE ONCOLOGY | 2015年 / 11卷 / 07期

关键词：

astronauts; cancer; chromosome aberrations; circadian disruptions; cockpit crew; cohort study; cosmic radiation; mortality; occupational exposure; pilots; FEMALE FLIGHT ATTENDANTS; CHROMOSOME-ABERRATION ANALYSIS; AIRLINE CABIN ATTENDANTS; BLOOD-LYMPHOCYTES; BREAST-CANCER; RISK-FACTORS; CYTOGENETIC DAMAGE; SPACE RADIATION; COCKPIT CREW; LIFE-STYLE;

D O I：

10.2217/fon.15.29

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cosmic radiation can cause genetic and cytogenetic damage. Certain occupations including airline pilots and cabin crew are acknowledged to have a greater exposure to cosmic radiation. In a systematic search of MEDLINE, performed from 1990 to 2014, we analyzed clinical studies using the keywords: cosmic radiation, cancer, chromosome aberration, pilots and astronauts. Increased incidence of skin cancers among airline cabin crew has been reported in a number of studies and appears to be the most consistent finding. However, as with other cancers, it is unclear whether increased exposure to cosmic radiation is a factor in the increased incidence or whether this can be explained by lifestyle factors. Further research is needed to clarify the risk of cancer in relation to cosmic radiation.

引用

页码：1123 / 1135

页数：13

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