Chromatographic Analysis of Bioactive Markers in Vidangarista, an Ayurvedic Polyherbal Formulation

被引：2
|
作者：
Bhujbal, Pallavi S. [1 ]
Sandhya, Parameswaran [1 ]
机构：
[1] Saraswathi Vidya Bhavans Coll Pharm, Dept Pharmacognosy, Dombivli E, Maharashtra, India
来源：
JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC | 2012年 / 25卷 / 01期
关键词：
High-performance thin-layer chromatography (HPTLC); Standardization; Vidangarista; Gallic acid; Conessine; Embelin;
D O I：
10.1556/JPC.25.2012.1.7
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Vidangarista is an ayurvedic polyherbal formulation officially recorded in the Ayurvedic formulary of India and used as an anthelmintic. The herbal formulation contains many plant constituents, and hence a large number of markers should be quantified to assess its quality. This paper reports the standardization of Vidangarista by HPTLC analysis for the presence of the biomarkers gallic acid and conessine. Each marker compound showed a linear relationship with an average r(2) = 0.99 in the concentration range studied. The proposed method was found to be precise, specific, and accurate, with a recovery of 99-101%, and hence can be used for routine analysis of this formulation.
引用
收藏
页码：42 / 47
页数：6
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