Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract

被引：18

作者：

Gorzalczany, Susana ^{[1
]}

Sulsen, Valeria ^{[2
]}

Redko, Flavia ^{[2
]}

Vescina, Cristina ^{[3
]}

Muschietti, Liliana ^{[2
]}

Martino, Virginia ^{[2
]}

Acevedo, Cristina ^{[1
]}

机构：

[1] Univ Buenos Aires, Fac Farm & Bioquim, Catedra Farmacol, RA-1113 Buenos Aires, DF, Argentina

[2] Univ Buenos Aires, Fac Farm & Bioquim, Catedra Farmacognosia, RA-1113 Buenos Aires, DF, Argentina

[3] Univ Buenos Aires, Fac Farm & Bioquim, Catedra Quim Analit, RA-1113 Buenos Aires, DF, Argentina

来源：

REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY | 2008年 / 18卷 / 01期

关键词：

Lippia integrifolia; verbenaceae; choleretic effect; antispasmodic effect;

D O I：

10.1590/S0102-695X2008000100005

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The aqueous extract of the aerial parts of Lippia integrifolia has been assayed for its choleretic and antispasmodic effects. Doses of 250, 500 and 750 mg/kg administered orally in rats significantly increased the bile flow and the bile acid output. The extract also showed a significant reduction of the contractions induced by acetylcholine, CaCl2 and KCl on isolated rat jejunum. The total caffeoyl quinic acids derivatives content, expressed as chlorogenic acid was 0.10% w/v by spectrophotometric determination.

引用

页码：16 / 20

页数：5

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